Epidemiological Methods in Life Course Research

By: Andrew Pickles (Editor), Barbara Maughan (Editor), Michael Wadsworth (Editor)

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Paperback | 1 August 2007

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274 Pages

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24.41 x 16.99 x 1.47

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Life course epidemiology is concerned with the origins of risk, resilience, and the processes of ageing, and how this information can be of value in a public health context - particularly for preventive health care. Its challenge is to discover, develop and analyse sources of data that cover
many years of life, especially the early developmental period when, it is thought, some fundamental aspects of lifetime health begin. It also analyses genetic propensity and environmental exposures.

The rapid development of life course epidemiology, in parallel with new work on developmental biology and the biology of ageing, has bought innovative and ingenious methods of data collection. These require new methodological techniques for the design of observational and quasi-experimental studies
of life course pathways to adult health. This book describes these developments, together with arguments for improving the measurement of the social environment and its role in developing individual vulnerability or adaptation. The development of bio-bank large-scale population studies for the
investigation of genetic effects is discussed, alongside the challenges this creates for the epidemiologist. The changing design of studies, increasing flow of longitudinal data, management of data, analytic challenges, timing, and both traditional and more recent methods of managing these features
in the study of causality, are discussed.

Life course epidemiology has an essential role in developing methods to evaluate precisely the impact of interacting developmental, environmental, and genetic effects, knowledge of which is fundamental for the design of effective prevention strategies in public health, as well as for the advancement
of understanding in the broader spheres of health and medicine.

Industry Reviews

Persons interested in life-course epidemiology wtih benefit greatly from reading this book. Throughout, the authors appropriately emphasize the strong connections betweent eh current construct of life-course epidemiology and vigorous research traditions in epidemiology, biology, psychology and the social sciences. The interdisciplinary quality of the book is especially welcome...in conjunction wtih the othe two volumes in this Oxford series, this book is of interest to both experienced epidemiologist and those in training programs, in addition to life-course researchers in related fields. American Journal of Epidemiology ...the book conveys both the conceptual as well as the practical complexities and methodological challenges associated with a life-course approach...[and] presents those challenges and offers a comprehensive overview of the methods available to successfully meet them. International Journal of Epidemiology

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