Drug Selectivity

An Evolving Concept in Medicinal Chemistry

By: Norbert Handler (Editor), Helmut Buschmann (Editor), Raimund Mannhold (Editor), JÃ¶rg Holenz (Editor)

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Hardcover | 5 December 2017 | Edition Number 1

At a Glance

Hardcover
536 Pages

Dimensions(cm)
25.15 x 17.53 x 2.79

Hardcover

$425.75

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The book "Drug Selectivity - An Evolving Concept in Medicinal Chemistry" provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process.
The result is a broad survey of current and future strategies for drug selectivity in medicinal chemistry with theoretical but also practical aspects. Different strategies are presented and evaluated, such as various design approaches, merged multiple ligands, discovery technologies and a broad range of successful examples of unselective drugs taken from all major disease areas. With its wide-ranging view of an emerging new paradigm in drug development, this handbook is of prime importance for every medicinal and pharmaceutical chemist.

Industry Reviews

In summary, this is a very good and valuable book for graduate students as well as medicinal chemists in academia and pharmaceutical companies. Readers will find many interesting chapters, some of which are more oriented to experts, while others are well suited for beginners. I recommend this book to those working in the field of medicinal chemistry, or even pharmacology, who have a particular interest in selective and selectively nonselective drugs.
(Prof. Antonio Macchiarulo, ChemMedChem 19/2018)

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