Dr. NO

The Discovery That Led to a Nobel Prize and Viagra

By: Louis Ignarro PhD

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Hardcover | 10 May 2022

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In 1998, Dr. Louis J. Ignarro was awarded a rare and coveted Nobel Prize for his groundbreaking discovery of nitric oxide (NO) and its many critically important biological actions. But his work goes far beyond the development of Viagra. It has never been more urgently relevant to the world than it is today, as clinical trials are underway that involve using inhaled NO to treat patients suffering from COVID-19.

Most Nobel laureate books have focused on the science. But in this fascinating and timely memoir, Dr. Ignarro opens up and shares intimate details about himself and his journey, his amazing accomplishments and heartbreaking setbacks, both in science and in life. This isn't just a scientist's story, it's a quintessentially American story. Only in America could the child of uneducated Italian immigrants start out a struggling student barely able to speak English, and go on to win the Nobel Prize.

Industry Reviews

"The discovery of Nitric Oxide by Lou Ignarro, and the role that it plays in reducing the risk of cardiovascular disease, is as important as the discovery of penicillin and insulin." David Heber, M.D., Ph.D., Director, UCLA Center for Human Nutrition
"Lou Ignarro's transfixing, riveting, true story takes you through a Horatio Alger tale as the son of immigrant parents in Brooklyn to a Nobel Prize in Medicine in Stockholm. The story reveals an uncanny parallel between Lou's life and that of Alfred Nobel himself, for whom the Prize is named -- both experimenting with the chemistry of 'nitro' compounds -- in the case of Nobel, harnessing these compounds as the explosive dynamite, and for Ignarro discovering nitroglycerin-like compounds' function in the human body as vasodilators. The one difference -- Lou doesn't blow up his laboratory!" Stuart Lipton, MD, PhD, Professor of Neuroscience, Scripps Clinic, La Jolla, California
"Lou Ignarro elegantly describes the uphill and circuitous path taken from building sand castles on the beach in New York to receiving the Nobel Prize from the King of Sweden." Sir Richard Roberts, PhD, biochemist and molecular biologist, New England Biolabs, Nobel Prize in Physiology or Medicine (1993)

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