Depression

Treatment Strategies and Management

By: Thomas L. Schwartz (Editor), Timothy J. Petersen (Editor)

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Hardcover | 1 April 2006 | Edition Number 1

At a Glance

Hardcover
320 Pages

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22.9 x 15.2 x 1.91

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Published: 1st September 2009

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Guiding clinicians toward the most effective treatment regimens, this reference offers detailed coverage of the symptomatology, diagnosis, epidemiology, and etiology of depression. A must-have tool for anyone prescribing psychotropics or performing psychotherapy, this source expertly reviews research and clinical data regarding acute and long-term outcomes, combination therapies, neuroimaging, genetics, and pharmacologic and psychotherapeutic measures to stand as the most complete layout of practices in the management of depression.

Industry Reviews

"...a nice balance between a review of what the evidence shows and practical advice and suggestions based on that review. It also focuses on difficult to treat cases, situations where combining medications or trying newer somatic therapies might be in order. I particularly liked when authors attempted to criticize the studies (instead of just summarizing them)....a very digestible review of what is considered state-of-the-art in the management of major depression."
-Doody's Review Services

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You Can Find This Book In

Non-Fiction Psychology Abnormal Psychology Medicine Clinical & Internal Medicine Neurology & Clinical Neurophysiology Medicine in General Other Branches of Medicine Psychiatry Therapy & Therapeutics Sleep Disorders & Therapy Family & Health

Coping with / Advice about Personal, Social & Health Topics Coping with / Advice about Illness & Specific Health Conditions Pharmacology

Foreword	p. v
Preface	p. vii
Contributors	p. xv
Epidemiology, Symptomatology, and Diagnosis	p. 1
Introduction	p. 1
Phenomenology of Depressive States	p. 2
Classification of the Depressive States	p. 4
Differential Diagnosis of the Depressive States	p. 5
Epidemiological Information	p. 6
References	p. 7
Substrates of Sadness: The Pathophysiology of Depression	p. 9
Introduction	p. 9
Historical Development of a Biological Approach to Depression	p. 10
Clues and Challenges to Exploring the Neurobiological Basis of Depression	p. 12
The Biogenic Amine Hypotheses: Signaling the Ascendancy of Biological Models of Depression	p. 14
Fast-Acting Neurotransmitters: Small Molecules with Big Roles	p. 20
Intracellular Signal Transduction: Taking in the Message	p. 22
Neuroendocrinology: Brain-Body Interactions	p. 23
Genetic Contributions: Risk and Resilience	p. 29
Conclusions	p. 31
References	p. 31
Drug Development, Psychotherapy Development, and Clinical Use	p. 41
Introduction	p. 41
Pharmacotherapy	p. 41
TCA and Tetracyclic Antidepressants	p. 42
MAOI Antidepressants	p. 46
NDRI Antidepressants	p. 48
SSRIs	p. 50
Trazodone	p. 53
Nefazodone	p. 54
Selective SNRIs	p. 55
Mirtazapine	p. 58
Conclusions	p. 59
Psychotherapy	p. 59
History of Depression-Focused Psychotherapies	p. 60
Overview of Depression-Focused Psychotherapies	p. 64
Conclusions	p. 71
References	p. 73
Treatment Outcomes with Acute Pharmacotherapy/Psychotherapy	p. 85
Introduction	p. 85
Acute Treatment Outcomes with Antidepressant Pharmacotherapy	p. 86
Acute Treatment Outcome with Psychotherapy	p. 97
Conclusions	p. 108
References	p. 109
Depression: Treatment Outcomes with Long-Term Maintenance	p. 123
Pharmacotherapy	p. 123
Predictors of Chronicity, Relapse, and Recurrence	p. 124
Drug Discontinuation	p. 125
Maintenance Pharmacotherapy	p. 127
Studies of Long-Term Pharmacotherapy	p. 128
Psychotherapy	p. 136
Residual Symptoms of Unipolar Depression	p. 138
Psychotherapy During Continuation and Maintenance Phases of Treatment	p. 139
Efficacy of the Sequential Approach in Treating Residual Symptoms	p. 141
Standard Format of Sequential Treatment Sessions	p. 143
Cognitive-Behavioral Treatment of Residual Symptoms	p. 144
Well-Being Therapy	p. 145
Lifestyle Modification	p. 149
Drug Tapering and Discontinuation	p. 149
Conclusions	p. 150
References	p. 150
Combining Medications to Achieve Remission	p. 161
Introduction	p. 161
Making the Decision to Switch, Combine, or Augment an Antidepressant	p. 164
Documentation During the Management of Combination Strategies	p. 167
Augmentation	p. 168
Antidepressant Combinations	p. 185
Conclusion	p. 191
References	p. 192
Combining Drug Treatments to Achieve Better Tolerability and Adherence	p. 201
Introduction	p. 201
Adjunctive Strategies	p. 202
Switching Antidepressants Owing to Intolerance	p. 206
References	p. 207
Depression and Genetics	p. 217
Introduction	p. 217
Limitations in Psychiatric Genetics	p. 217
Traditional Genetic Approaches	p. 218
Genetic Epidemiology	p. 219
Candidate Genes	p. 222
Conclusion	p. 224
References	p. 224
Depression, Neuroimaging and Neurophysiology	p. 229
Introduction	p. 229
Structural Imaging	p. 230
Functional Imaging	p. 232
Magnetic Resonance Spectroscopy	p. 234
EEG Studies	p. 237
References	p. 239
Depression and Somatic Treatments	p. 245
Introduction	p. 245
ECT, TMS, and MST in the Treatment of Major Depression	p. 246
ECT in MDD	p. 247
TMS in MDD	p. 251
MST in MDD	p. 253
Minimally Invasive Somatic Techniques in MDD: DBS and VNS	p. 254
Deep Brain Stimulation (DBS)	p. 258
VNS	p. 261
Conclusions	p. 268
References	p. 270
Medication and Psychotherapy Options and Strategies: The Future	p. 283
Introduction	p. 283
Combining Psychotherapy and Antidepressant Medications: Sequential Application	p. 283
Conceptual Shift from Cognitive Content to Cognitive Process	p. 284
Dismantling and Integrating Treatments	p. 285
Interpersonal Psychotherapy	p. 286
Specialized Populations	p. 286
Dissemination of Evidence-Based Treatments	p. 286
Psychodynamic Treatment Models: What's Next?	p. 287
Balancing Effectiveness and Efficacy Research	p. 287
Improving Detection of MDD	p. 288
Use of Target Symptom Problem Lists and Pharmacodynamic Theory	p. 288
Manualization of Psychopharmacopsychotherapy	p. 289
Technology	p. 289
Pharmacotherapy	p. 289
Conclusions	p. 291
Bibliography	p. 292
Index	p. 293
Table of Contents provided by Ingram. All Rights Reserved.

Depression

Treatment Strategies and Management

At a Glance

New Edition

Hardcover

Industry Reviews

Shipping

How to return your order

Defective items

You Can Find This Book In

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