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Current Cancer Research

By: Ram Datar (Editor), Richard J. Cote (Editor)

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Paperback | 30 March 2018

At a Glance

Paperback
360 Pages

Dimensions(cm)
23.5 x 15.5 x 1.91

Paperback

$249.00

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This volume provides the latest research on circulating tumor cells aimed for cancer researchers, scientists, and molecular oncologists. It presents the basic concepts behind circulating tumor cells (CTCs), metastatic biology, and potential applications as to how CTCs can be used in diagnostic biomarkers.
CTCs are cells that have detached from the primary tumor and circulate in the bloodstream. Such cells may become "seeds" for the growth of additional tumors. The field of analysis surrounding cancer metastasis has been steadily growing, and CTCs provide effective biomarkers that can be examined in peripheral blood through a minimally invasive "liquid biopsy" procedure. CTCs offer several exciting applications, not only as markers of disease progression but also as biomarkers of monitoring response to therapy and companion diagnostics for novel anticancer drug development. In recent years there has been rapid growth and worldwide developments on CTCs, which span both the basic sciences and biomedical engineering fields.

Industry Reviews

"The book will prove to be a useful resource for graduate students and established researchers with an interest in this field. It can provide a definitive source for the much-needed but often neglected theoretical framework for hospitals and laboratories desirous of establishing a CTC assay, in addition to providing practical tips. It should be included in the collection of libraries that cater to oncology clinicians, laboratory personnel as well as basic researchers." (Sudeep Gupta, The National Medical Journal of India, Vol. 30 (1), January-February, 2017)

"The book is divided into four chapters that beyond of methodological issues summarize comprehensive information on biological nature, genesis, molecular characteristics, alterations, behaviour and clinical utility of CTCs. ... 'Circulating tumour cells' brings us comprehensive review of current state-of-art in methodological approaches, clinical application and future perspectives of CTCs research." (Bozena Smolkova, Neoplasma, Vol. 63 (5), 2016)

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