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Cell-Based Biosensors

By: Jaroslav Racek

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Hardcover | 9 December 1995 | Edition Number 1

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SOME ADVANTAGES OF CELL-BASED BIOSENSORS:
Isolation, purification, and immobilization of enzymes are often very difficult; these can be omitted with cell-based biosensors.
Some enzymes can lose their activity during isolation or immobilization; this risk is eliminated by the use of whole cells.
Enzymes in the cell's natural environment are usually extremely stable.
Multi-step enzyme reactions in intact cells can be used, making it possible to avoid the preparation of complicated artificial multi-enzyme systems.
Coenzymes and activators are often present in the cells, and thus, it is not necessary to add them into the system; the cell itself usually cares for their effective regeneration.

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