Calcium and Phosphate Metabolism Management in Chronic Renal Disease

Cover -- Contents -- Contributors -- Preface -- Chapter 1: Historical Perspective of Calcium Management in Patients with Chronic Renal Diseases -- I. Introduction -- II. Calcium Metabolism in Normal Subjects -- III. Calcium Metabolism in Patients with CRD -- A. Calcium Absorption in CRD Patients -- B. Management of Calcium in Renal Dialysis Patients -- C. Urinary Excretion of Calcium in CRD -- D. Calcium Metabolic Problems in Renal Transplant Patients -- E. Management of Calcium Metabolism in CRD Patients -- F. Conclusion -- Chapter 2: Disorders of Phosphorous Homeostasis in CKD -- I. Introduction -- II. Normal Phosphorus Homeostasis -- III. Intestinal Absorption -- IV. Renal Handling -- V. Bone Remodeling -- VI. Phosphatonins -- VII. Disorders of Pi in Non-CKD Patients -- A. Hypophosphatemia -- B. Hyperphosphatemia -- VIII. Disorders of Pi In CKD Patients -- IX. Dialytic Removal of Phosphate -- X. Consequences of Hyperphosphatemia -- XI. Conclusions -- Chapter 3: Pathogenesis and Management of Secondary Hyperparathyroidism -- I. Introduction -- II. Pathogenesis -- A. Role of Phosphate -- B. Phosphotonins -- III. Clinical Manifestations -- A. Bone Disease -- B. Calciphylaxis -- C. Vascular Calcification -- IV. Management of Secondary Hyperparathyroidism -- A. Phosphorus Control -- B. Dietary Phosphorus Restriction -- C. Phosphorus Binders -- D. Vitamin D Therapy -- E. Calcimimetics -- F. Parathryoidectomy -- V. Conclusion -- Chapter 4: Uremic Toxins in Chronic Renal Failure -- I. Introduction -- II. Uremic Solute Retention -- A. General Classification of Uremic Solutes -- B. Main Uremic Retention Products -- III. Conclusion -- Chapter 5: Calcitriol Metabolism and Action in Chronic Renal Disease -- I. Introduction -- II. Effect of Calcitriol on Various Organs -- A. Effect of Calcitriol on the Nervous System -- B. Effect of Calcitriol on Cardiac Function -- C. Effect of Calcitriol on the Parathyroid Gland -- D. Effect of Calcitriol on Colon Carcinogenesis -- E. Effect of Calcitriol on Prostate Cancer -- F. Effect of Calcitriol on Pulmonary Cancer -- G. Immunoregulatory Function of Calcitriol -- III. Calcitriol Production in Chronic Renal Disease -- A. Decreased Renal Tissue -- B. Hyperphosphatemia -- C. Metabolic Acidosis -- D. Extrarenal Production of Calcitriol -- E. Uremic Toxins -- F. Purine Derivatives -- G. Parathyroid Hormone (PTH) -- H. Effect of Glucose on the Function of the Calcitriol Receptor and Vitamin D Metabolism -- IV. Metabolic Degradation of Calcitriol in Renal Failure -- V. Reduced Calcitriol Receptor Concentration in Chronic Renal Disease -- VI. Hormone-Receptor Interaction with Nuclear Chromatin Is Decreased in Chronic Renal Failure -- VII. Secondary Hyperparathyroidism and Calcitriol -- VIII. Effect of Uremia on Other Members of the Steroid Hormone Receptor Superfamily -- IX. Conclusion -- Chapter 6: Renal Osteodystrophy -- I. Introduction -- II. Classification of Bone Disease -- III. Clinical Manifestations -- IV. O.