| Preface | p. xi |
| Done Is Good | p. xiv |
| Structure and Pedagogy | p. xvi |
| Notes and Commentary | p. xix |
| Acknowledgments | p. xxi |
| Bioethics Questions Posed in Text | p. xxiii |
| Prologue: Bioethics - Discovery through Design | |
| A Different Approach to Bioethics | p. 3 |
| Arguments for and Against Case Analysis | p. 4 |
| Driver's Education Analogy | p. 5 |
| Example Case: Priming the Pump | p. 6 |
| Case Analysis | p. 7 |
| Notes and Commentary | p. 8 |
| Bioethics: A Creative Approach | |
| Thought Experiments | p. 10 |
| Teachable Moment: Trust | p. 12 |
| The Principle of Double Effect | p. 12 |
| Teachable Moment: The Engineer as Agent versus Judge | p. 12 |
| Amy the Engineer | p. 15 |
| Teachable Moment: Who Was Van Rensselaer Potter? | p. 18 |
| Credat Emptor | p. 18 |
| Teachable Moment: Capital Punishment, Abortion, and the Definition of Human Life | p. 20 |
| The Good Engineer | p. 21 |
| Feedback and Enhancement of Design | p. 22 |
| Teachable Moment: The Good Engineer | p. 24 |
| The Profession of Engineering | p. 25 |
| Engineering Bioethics and Morality | p. 26 |
| Discussion Box: Ethics and the Butterfly Effect | p. 27 |
| "Small" Error and Devastating Outcomes | p. 28 |
| Technology, Engineering, and Economics | p. 28 |
| Teachable Moment: The Dismal Scientist versus the Technological Optimist | p. 31 |
| Engineering Competence | p. 39 |
| Engineering: Both Integrated and specialized | p. 39 |
| Who Is a Professional? | p. 40 |
| What Is Technical? | p. 41 |
| Systematics: Incorporating Ethics into the Design Process | p. 42 |
| Notes and Commentary | p. 43 |
| Bioethics and the Engineer | |
| Major Bioethical Areas | p. 51 |
| Cloning and Stem Cell Research | p. 52 |
| Teachable Moment: Nanog | p. 56 |
| Human Enhancement | p. 57 |
| Patenting Life | p. 57 |
| Teachable Moment: Patenting Germplasm | p. 58 |
| Neuroethics | p. 59 |
| Organ Transplantation | p. 60 |
| Responsible Conduct of Human Research | p. 60 |
| Animal Testing | p. 61 |
| Is the Research Worth It? | p. 63 |
| Systematic Reality Check | p. 66 |
| Genetically Modified Organisms | p. 67 |
| Transgenic Species | p. 68 |
| Food | p. 68 |
| Environmental Health: The Ethics of Scale and the Scale of Ethics | p. 70 |
| Temporal Aspects of Bioethical Decisions: Environmental Case Studies | p. 70 |
| Agent Orange | p. 71 |
| Japanese Metal Industries | p. 74 |
| Minamata Mercury Case | p. 74 |
| Cadmium and Itai Itai Disease | p. 75 |
| Scale Is More than Size | p. 77 |
| Love Canal | p. 78 |
| Times Beach | p. 79 |
| Teachable Moment: The Whole Is Greater than the Sum of Its Parts | p. 80 |
| Active Engineering | p. 81 |
| Ethical Theories: A Primer | p. 83 |
| Truth | p. 84 |
| Psychological Aspects of Ethics | p. 86 |
| Teachable Moment: The Physiome Project: The Macroethics of Engineering toward Health | p. 89 |
| Fairness | p. 94 |
| Value as a Bioethical and Engineering Concept | p. 95 |
| Technical Optimism versus Dismal Science | p. 96 |
| Notes and Commentary | p. 98 |
| An Engineered Future: Human Enhancement | |
| Professional Zeitgeist: How Engineers Think | p. 106 |
| Improvement versus Enhancement | p. 109 |
| Engineering Intuition | p. 111 |
| Engineers versus Economists | p. 112 |
| Intuiting Value | p. 113 |
| Deductive and Inductive Reasoning: Precursors to Intuition | p. 114 |
| Creativity | p. 116 |
| Moral Coherence | p. 120 |
| Creativity and Bioethics | p. 122 |
| The Ethical Quandary of Enhancement | p. 124 |
| Scientific Dissent | p. 126 |
| Notes and Commentary | p. 134 |
| The Bioethical Engineer | |
| Professional Trust | p. 139 |
| Codes of Ethics: Words to Live By | p. 142 |
| Discussion Box: The Code of Hammurabi | p. 143 |
| Limitations of Codes of Ethics | p. 147 |
| Risk Shifting: Organochlorine Pesticides | p. 147 |
| Right of Professional Conscience | p. 152 |
| Groupthink and the Right of Conscience | p. 156 |
| Animals and Engineers | p. 158 |
| Teachable Moment: Confined Animal Feeding Operations and the Moral Standing of Animals | p. 159 |
| Making Ethical Decisions in Engineering | p. 160 |
| Discussion Box: Four Persons Who Changed the Way We Think about Nature | p. 162 |
| John Muir | p. 162 |
| Rachel Carson | p. 162 |
| Christopher Stone | p. 163 |
| Gaylord Nelson | p. 164 |
| Notes and Commentary | p. 164 |
| Bioethical Research and Technological Development | |
| Beyond Regulation | p. 169 |
| Integrity | p. 169 |
| Teachable Moment: The Therapeutic Misconception | p. 173 |
| The Experiment | p. 173 |
| The Hypothetico-Deductive Method | p. 174 |
| Research Conflict of Interest | p. 175 |
| Teachable Moment: Truth and Turtles | p. 176 |
| Professionalism | p. 178 |
| Technology: Friend and Foe | p. 178 |
| Teachable Moment: Medical Device Risk | p. 179 |
| Risk Homeostasis and the Theory of Offsetting Behavior | p. 180 |
| Artifacts | p. 182 |
| Automation and Mechanization of Medicine | p. 183 |
| Professional Consideration: Do Engineers Have Patients? | p. 184 |
| Technological Reliability | p. 185 |
| Low Tech Engineering | p. 189 |
| Information Technology | p. 190 |
| The Ethics of Nanotechnology | p. 193 |
| Notes and Commentary | p. 195 |
| Bioethical Success and Failure | |
| Teachable Moment: Engineering Measurement | p. 201 |
| Measurements of Success and Failure | p. 203 |
| Technological Success and Failure | p. 203 |
| Risk as a Bioethical Concept | p. 205 |
| Safety, Risk, and Reliability in Design | p. 206 |
| Probability: The Mathematics of Risk and Reliability | p. 206 |
| Discussion Box: Choose Your Risk | p. 210 |
| Reliability: An Ethics Metric | p. 214 |
| Reducing Risks | p. 217 |
| Risk as an Ethical Concept | p. 220 |
| Risk-Based Ethics: The Syllogism Revisited | p. 223 |
| Causation | p. 225 |
| Biographical Box: Sir Bradford Hill | p. 226 |
| Notes and Commentary | p. 228 |
| Analyzing Bioethical Success and Failure | |
| Medical Device Failure: Human Factors Engineering | p. 232 |
| Teachable Moment: How to Analyse a Medical Device | p. 233 |
| Utility as a Measure of Success | p. 234 |
| Mistakes and Miscalculations | p. 236 |
| Extraordinary Natural Circumstances | p. 236 |
| Critical Path | p. 237 |
| Negligence | p. 243 |
| Lack of Imagination | p. 244 |
| Bioterrorism: The Engineer's Response | p. 244 |
| Dual Use and Primacy of Science | p. 246 |
| Social Response of Engineering to Terrorism | p. 248 |
| Success Paradigms | p. 248 |
| Characterizing Success and Failure | p. 249 |
| Accountability | p. 249 |
| Value | p. 250 |
| Case Analysis | p. 250 |
| Notes and Commentary | p. 258 |
| Justice and Fairness as Biomedical and Biosystem Engineering Concepts | |
| Fairness and Distributive Justice | p. 263 |
| Discussion Box: Harm and the Hippocratic Oath | p. 271 |
| Teachable Moment: Disposal of a Slightly Hazardous Waste | p. 272 |
| Solution and Discussion | p. 272 |
| Though Experiment: Who Is More Ethical? | p. 274 |
| Professional Virtue and Empathy | p. 277 |
| Teachable Moment: Albert Schweitzer and the Reverence for Life | p. 277 |
| Reason | p. 279 |
| Teachable Moment: Abortion, Fairness, and Justice | p. 280 |
| Utility | p. 281 |
| Teachable Moment: Utility and Futility | p. 283 |
| Precaution as a Bioethical Concept | p. 285 |
| Discussion Box: The Tragedy of the Commons | p. 286 |
| Notes and Commentary | p. 287 |
| Sustainable Bioethics | |
| Green Is Good | p. 291 |
| Sustainability | p. 292 |
| Teachable Moment: Rational Ethics and Thermodynamics | p. 293 |
| Life Cycles and Concurrent Engineering | p. 300 |
| Case Study Box: SIDS, A Concurrent Engineering Failure | p. 301 |
| Discussion Box: The Coffee Cup Debate | p. 305 |
| The Bioethics of Combustion | p. 307 |
| Systematic Bioethics | p. 317 |
| Seveso Plant Disaster | p. 318 |
| Poverty and Pollution | p. 320 |
| Interdependence | p. 322 |
| Notes and Commentary | p. 323 |
| Engineering Wisdom | |
| Ethics and Chaos | p. 329 |
| Macroethics and Microethics | p. 330 |
| Future Directions | p. 331 |
| The Humble Engineer | p. 338 |
| Notes and Commentary | p. 340 |
| Epilogue: Practical Bioethics | |
| Shutting Down the Pump | p. 343 |
| Objectivity and Finding Truth | p. 344 |
| Moral Courage | p. 346 |
| Bioethics Resources for the Engineer | p. 347 |
| Suggested Readings | p. 348 |
| Ethics of Emerging Technologies | p. 348 |
| Ethical Analysis, Reasoning, and Decision Making | p. 349 |
| Macroethics and Societal Risk | p. 349 |
| Teaching Engineering Macroethics | p. 351 |
| Teaching Engineering Microethics | p. 353 |
| Useful Websites | p. 354 |
| Notes and Commentary | p. 356 |
| p. 357 |
| p. 363 |
| Glossary of Terms Likely to Be Encountered in Bioethical Decision Making | p. 365 |
| Name Index | p. 395 |
| Subject Index | p. 397 |
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