| Bioactive Materials and Processing | p. 1 |
| Introduction | p. 1 |
| Calcium Phosphate Ceramics | p. 3 |
| Biological Apatites | p. 4 |
| Hydroxyapatite | p. 5 |
| Tricalcium Phosphate | p. 22 |
| Other Calcium Phosphate Compounds | p. 26 |
| Bioactive Glasses and Glass-Ceramics | p. 27 |
| Bioglass | p. 27 |
| Cerabone | p. 33 |
| Other Bioactive Glasses and Glass-Ceramics | p. 37 |
| Bioactive Coatings | p. 40 |
| Plasma Sprayed Hydroxyapatite Coatings | p. 40 |
| Calcium Phosphate Coatings by Ion Beam Sputter Deposition | p. 52 |
| Bioactive Functionally Graded Coatings | p. 53 |
| Bioactive Composites | p. 55 |
| Bioactive Composites for Tissue Replacement and Regeneration | p. 55 |
| Bioactive Bone Cement | p. 66 |
| Bioactive Ceramic Matrix Composites | p. 68 |
| Bioactive Metal Matrix Composites | p. 70 |
| Concluding Remarks | p. 71 |
| Acknowledgements | p. 72 |
| References | p. 72 |
| Biocompatibility of Materials | p. 83 |
| Introduction | p. 83 |
| Overview | p. 83 |
| Definitions and Concepts | p. 84 |
| Applications of Biomaterials | p. 86 |
| The Host Responses to Materials | p. 89 |
| Protein Adsorption | p. 89 |
| Cell Adhesion | p. 90 |
| Blood Clotting/Coagulation | p. 92 |
| Tissue Response | p. 97 |
| Biological Performance of Biomaterials | p. 99 |
| Swelling and Leaching | p. 99 |
| Corrosion | p. 100 |
| Particulates | p. 101 |
| Surface Topography | p. 102 |
| Biocompatibility Assessment | p. 104 |
| First Level Tests: Biosafety Testing | p. 105 |
| Second Level Tests: Biofunctional Testing | p. 108 |
| Protein Adsorption at Interfaces | p. 111 |
| Concepts of Adsorption | p. 112 |
| Protein Adsorption at Interfaces | p. 112 |
| Thermodynamics | p. 113 |
| Transport Theory | p. 114 |
| Adsorption Theory | p. 115 |
| Factors Influencing Protein Adsorption | p. 117 |
| Surface Modifications for Enhanced Biocompatibility | p. 119 |
| Introduction to Surface Modification | p. 119 |
| Surface Characterization | p. 120 |
| Applications of PEG Surface Modification | p. 121 |
| Characteristics of PEG Coatings | p. 125 |
| PEG Surface Modification | p. 126 |
| Future Directions | p. 133 |
| Biocompatibility Assessment at the Molecular Level | p. 134 |
| Surface Modification Protocols for Improved Biocompatibility and Applications in Biotechnology | p. 136 |
| References | p. 137 |
| Biotechnological Applications of Inorganic Glasses | p. 145 |
| The Nature of Inorganic Glass | p. 145 |
| Why Inorganic Glasses? | p. 146 |
| Homogeneity | p. 146 |
| Compositional Flexibility | p. 147 |
| Flexibility in Manufacturing | p. 147 |
| Surface Modification | p. 148 |
| Other Modifications | p. 149 |
| Properties Pertinent to Biotechnology and Biomedicine | p. 150 |
| Chemical Durability | p. 150 |
| Surface Chemistry | p. 153 |
| Optical Properties | p. 155 |
| Mechanical Properties | p. 158 |
| Thermal, Electric, and Magnetic Properties | p. 159 |
| Summary | p. 160 |
| References | p. 160 |
| Biocomposite Materials for Biotechnology | p. 163 |
| Introduction | p. 163 |
| High-Performance Titanium Phosphates | p. 165 |
| Preparation Procedures of Porous Glass-Ceramics | p. 166 |
| Porous Glass-Ceramics for Immobilization of Enzymes | p. 168 |
| Immobilization of Enzymes and Measurement of Activity | p. 169 |
| Immobilization of [beta]-Galactosidase | p. 170 |
| Immobilization of Alkalophilic Proteinase | p. 171 |
| Availability of Porous CaTi[subscript 4] (PO[subscript 4])[subscript 6] Glass-Ceramics | p. 172 |
| Porous Glass-Ceramics with Bacteriostatic Activity | p. 173 |
| Silver-Containing Porous Glass-Ceramics | p. 173 |
| Porous Glass-Ceramics with a Skeleton of Copper Titanium Phosphate | p. 180 |
| Porous Glass-Ceramics with an Integrated Skeleton | p. 185 |
| Preparation Procedure | p. 186 |
| Functions of Glass-Ceramics | p. 188 |
| Concluding Remarks | p. 190 |
| References | p. 192 |
| Tissue Engineering | p. 195 |
| Introduction | p. 195 |
| Tissue Engineering Approaches | p. 197 |
| Cells Used in Tissue Engineering | p. 198 |
| Biomaterials for Tissue Engineering | p. 199 |
| Polymeric Biomaterials | p. 199 |
| Metals | p. 208 |
| Ceramics | p. 208 |
| Ceramic/Polymer Composite Biomaterials | p. 209 |
| Tissue Engineering of Skin | p. 215 |
| Regeneration of the Epidermis | p. 216 |
| Regeneration of the Dermis | p. 217 |
| Living Skin Equivalent | p. 218 |
| Tissue Engineering of Bone | p. 219 |
| Bone Growth Induction | p. 221 |
| Cell Delivery | p. 223 |
| Tissue Engineering of the Peripheral Nervous System | p. 225 |
| Materials | p. 226 |
| Methods for Promoting Nerve Regeneration Inside NGCs | p. 228 |
| Tissue Engineering of the Heart Valve | p. 230 |
| Future Challenges | p. 233 |
| References | p. 234 |
| Index | p. 245 |
| Table of Contents provided by Rittenhouse. All Rights Reserved. |