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Applied Surrogate Endpoint Evaluation Methods with SAS and R : Chapman & Hall/CRC Biostatistics Series - Ariel  Alonso

Applied Surrogate Endpoint Evaluation Methods with SAS and R

By: Ariel Alonso, Ziv Shkedy, Wim Van der Elst, Tomasz Burzykowski, Theophile Bigirumurame

Paperback | 18 December 2020 | Edition Number 1

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An important factor that affects the duration, complexity and cost of a clinical trial is the endpoint used to study the treatment's efficacy. When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.

Industry Reviews

"This is a timely text. The number of published studies using surrogate endpoints has increased dramatically since the early work of the 1980s; however, there is a dearth of available texts or software on this topic. Anyone with an interest in surrogate endpoint evaluation would benefit from this text."
~Statistics in Medicine

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