Agrobacterium

From Biology to Biotechnology

By: Tzvi Tzfira (Editor), Vitaly Citovsky (Editor)

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Hardcover | 1 February 2008

At a Glance

Hardcover
788 Pages

Dimensions(cm)
23.5 x 15.5 x 3.81

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Agrobacterium is a plant pathogen which causes the "crown-gall" disease, a neoplastic growth that results from the transfer of a well-defined DNA segment ("transferred DNA", or "T-DNA") from the bacterial Ti (tumor-inducing) plasmid to the host cell, its integration into the host genome, and the expression of oncogenes contained on the T-DNA. The molecular machinery, needed for T-DNA generation and transport into the host cell and encoded by a series of chromosomal (chv) and Ti-plasmid virulence (vir) genes, has been the subject of numerous studies over the past several decades. Today, Agrobacterium is the tool of choice for plant genetic engineering with an ever expanding host range that includes many commercially important crops, flowers, and tree species. Furthermore, its recent application for the genetic transformation of non-plant species, from yeast to cultivated mushrooms and even to human cells, promises this bacterium a unique place in the future of biotechnological applications.

The book is a comprehensive volume describing Agrobacterium's biology, interactions with host species, and uses for genetic engineering.

Industry Reviews

From the reviews:

"A compilation of many aspects of Agrobacterium research, with each chapter authored by experts in the field. Though the book is heavily oriented toward the genetic/molecular basis of the gene transfer process, it includes the history of Agrobacterium research, nomenclature, and basic biology of the bacterial/plant interaction. The final chapters review bioethics and legal aspects of Agrobacterium-mediated gene transfer. Summing Up: Recommended. Graduate students and researchers/faculty." (L. M. Baird, CHOICE, Vol. 45 (11), August, 2008)

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Symbiotic Nitrogen Fixation : Proceedings of the 14th North American Conference on Symbiotic Nitrogen Fixation, University of Minnesota, St. Paul Minnesota, U. S. A. July 25-29, 1993

Agrobacterium : a disease-causing bacterium
A brief history of research on Agrobacterium tumefaciens : 1900-1980s
Agrobacterium and plant biotechnology
The Agrobacterium tumefaciens C58 genome
Agrobacterium - taxonomy of plant-pathogenic Rhizobium species
The initial steps in Agrobacterium tumefaciens pathogenesis : chemical biology of host recognition
Agrobacterium-host attachment and biofilm formation
Production of a mobile T-DNA by Agrobacterium tumefaciens
Translocation of oncogenic T-DNA and effector proteins to plant cells
Intracellular transport of Agrobacterium T-DNA
Mechanisms of T-DNA integration
Agrobacterium tumefaciens-mediated transformation : patterns of T-DNA integration into the host genome
Function of host proteins in the Agrobacterium-mediated plant transformation process
The oncogenes of Agrobacterium tumefaciens and Agrobacterium rhizogenes
Biology of crown gall tumors
The cell-cell communication system of Agrobacterium tumefaciens
Horizontal gene transfer
Agrobacterium-mediated transformation of non-plant organisms
The bioethics and biosafety of gene transfer
Agrobacterium-mediated gene transfer : a lawyer's perspective
Index
Table of Contents provided by Blackwell. All Rights Reserved.

Agrobacterium

From Biology to Biotechnology

At a Glance

Hardcover

Industry Reviews

Shipping

How to return your order

Defective items

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