| Contributors | p. ix |
| Preface | p. xiii |
| Genetics of Morphogenesis and Pathogenic Development of Ustilago maydis | p. 1 |
| Introduction | p. 3 |
| Mating | p. 4 |
| Dimorphism | p. 12 |
| Cell Cycle and Cytoskeletal Regulation | p. 17 |
| Pathogenesis | p. 21 |
| Genome-Wide Approaches for the Study of U. maydis | p. 27 |
| The Plant Side of the Disease Equation | p. 36 |
| Conclusion | p. 38 |
| References | p. 38 |
| Enabling a Community to Dissect an Organism: Overview of the Neurospora Functional Genomics Project | p. 49 |
| Introduction | p. 51 |
| Project 1: Systematic Gene Knockouts | p. 56 |
| Project 2: Genome Informatics and Functional Annotation Studies | p. 71 |
| Project 3: Profiling Transcription in Neurospora | p. 78 |
| Project 4: cDNA Libraries and the Generation of a High-Density SNP Map | p. 85 |
| Conclusions | p. 93 |
| References | p. 93 |
| Genomics of the Plant Pathogenic Oomycete Phytophthora: Insights into Biology and Evolution | p. 97 |
| Introduction | p. 98 |
| Advances in Structural Genomics | p. 100 |
| Organization of Phytophthora Genomes | p. 104 |
| Other Genetic Elements | p. 114 |
| Tools for Functional Genomics | p. 115 |
| Selected Areas of Phytophthora Research | p. 118 |
| Conclusions and Prospects | p. 131 |
| References | p. 132 |
| Sex and Virulence of Human Pathogenic Fungi | p. 143 |
| The Predominant Human Pathogenic Fungi | p. 144 |
| Sex in Fungal Pathogens: Cost Versus Benefit | p. 146 |
| Mating-Type Loci Are the Sex-Determining Regions in Fungi | p. 148 |
| Sex in Cryptococcus | p. 149 |
| The Unusual Cryptococcus Mating-Type Locus | p. 153 |
| Genome Sequencing Identified Mating-Type Locus in the "Asexual" C. albicans and Led to the Discovery of Mating | p. 153 |
| Mating-Type Locus in A. fumigatus | p. 157 |
| Mating-Type Loci in Other Human Pathogenic Fungi | p. 157 |
| Population Genetic Studies in "Asexual" Fungi Reveal Evidence of Sex | p. 159 |
| The Role of Sex in Pathogenesis | p. 162 |
| Concluding Remarks | p. 165 |
| References | p. 166 |
| From Genes to Genomes: A New Paradigm for Studying Fungal Pathogenesis in Magnaporthe oryzae | p. 175 |
| Introduction | p. 176 |
| Attachment and Appressorium Morphogenesis | p. 177 |
| Mechanisms of Penetration | p. 187 |
| Invasive Growth and Host-Pathogen Interactions | p. 190 |
| Genes and Genome Features | p. 195 |
| Functional Genomics | p. 204 |
| Concluding Remarks | p. 208 |
| References | p. 209 |
| Genetic and Genomic Dissection of the Cochliobolus heterostrophus Tox1 Locus Controlling Biosynthesis of the Polyketide Virulence Factor T-toxin | p. 219 |
| Introduction | p. 220 |
| Tools for Genetic Analysis | p. 228 |
| C. heterostrophus and SCLB | p. 233 |
| The Genetics of T-Toxin Production | p. 235 |
| Genomic Analysis of the Tox1 Locus | p. 242 |
| The PM-Toxin Gene Cluster | p. 247 |
| Are Additional Tox Loci Involved in T-Toxin Production? | p. 249 |
| Model for Biosynthesis of T-Toxin | p. 250 |
| The Evolution of Polyketide-Mediated Fungal Specificity for T-Cytoplasm Corn | p. 252 |
| Conclusions | p. 254 |
| References | p. 255 |
| Fungal Genomics: A Tool to Explore Central Metabolism of Aspergillus fumigatus and Its Role in Virulence | p. 263 |
| Introduction | p. 264 |
| Nutritional Auxotrophy and Fungal Genetics | p. 265 |
| Regulation of Amino Acid Biosynthesis | p. 268 |
| Regulation of Ambient pH Response | p. 272 |
| Regulation of Nitrogen Response Pathways | p. 275 |
| Regulation of Carbon Response Pathways | p. 277 |
| Concluding Remarks | p. 281 |
| References | p. 281 |
| Index | p. 285 |
| Table of Contents provided by Ingram. All Rights Reserved. |
