Modularity in Development and Evolution

By: Gerhard Schlosser (Editor), Gunter P. Wagner (Editor)

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Hardcover | 1 July 2004 | Edition Number 1

At a Glance

Hardcover
600 Pages

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2.38 x 1.6 x 0.44

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"Modularity in Development and Evolution offers the first sustained exploration of modules from developmental and evolutionary perspectives. Contributors discuss what modularity is, how it can be identified and modeled, how it originated and evolved, and its biological significance. Covering modules at levels ranging from genes to colonies, the book focuses on their roles not just in structures but also in processes such as gene regulation. Among many exciting findings, the contributors demonstrate how modules can highlight key constraints on evolutionary processes.
A timely synthesis of a crucial topic, "Modularity in Development and Evolution shows the invaluable insights modules can give into both developmental complexities and their evolutionary origins.

Industry Reviews

""[This collection] is one of the most recent attempts at clarifying the concept of modularity and its implications for evolution. . . . The different contributions represent a variety of perspectives and examples of evolutionary and developmental modularity, and stand as a clear demonstration of just how difficult it can be to firmly formalize this 'fashionable' concept."

--Patricia Beldade "Quarterly Review of Biology"

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Non-Fiction Science Biology, Life Sciences Developmental Biology Life Sciences in General Evolution Science in General Miscellaneous Items

Contents
Introduction: The Modularity Concept in Developmental and Evolutionary Biology
The Molecular and Developmental Basis of Modularity
Selector Genes and the Genetic Control of Developmental Modules
The Basic Helix-Loop-Helix Proteins in Vertebrate and Invertebrate Neurogenesis
The Pax/Six/Eya/Dach Network in Development and Evolution
The Notch Signaling Module
Sonic Hedgehog and Wnt Signaling Pathways during Development and Evolution
Modular Pleiotropic Effects of Quantitative Trait Loci on Morphological Traits
Central Nervous System Development: From Embryonic Modules to Functional Modules
Recognition and Modeling of Modules
Synexpression Groups: Genetic Modules and Embryonic Development
Systematic Exploration and Mining of Gene Expression Data Provides Evidence for Higher-Order, Modular Regulation
Qualitative Analysis of Gene Networks: Toward the Delineation of Cross-Regulatory Modules
Exploring Modularity with Dynamical Models of Gene Networks
Basins of Attraction in Network Dynamics: A Conceptual Framework for Biomolecular Networks

Informational Accretion, Gene Duplication, and the Mechanisms of Genetic Module Parcellation
The Role of Genetic Architecture Constraints in the Origin of Variational Modularity
Generative Entrenchment, Modularity, and Evolvability: When Genic Selection Meets the Whole Organism
Starting the Segmentation Gene Cascade in Insects
The Evolution of Nematode Development: How Cells and Genes Change their Function
Modularity in the Evolution of Vertebrate Appendages
Individuals as Modules in Higher-Level Units
The Individual as a Module: Solitary-to-Colonial Transitions in Metazoan Evolution and Development
Evolvability, Modularity, and Individuality during the Transition to Multicellularity in Volvocalean Green Algae
Symbiosis, Evolvability, and Modularity
Synthesis
The Role of Modules in Development and Evolution
Contributors
Index
Table of Contents provided by Publisher. All Rights Reserved.

Modularity in Development and Evolution

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