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Information Approach To Mitochondrial Dysfunction, An : Extending Swerdlow's Hypothesis - Rodrick Wallace

Information Approach To Mitochondrial Dysfunction, An

Extending Swerdlow's Hypothesis

By: Rodrick Wallace

eText | 13 February 2015

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The monograph applies sophisticated topological symmetry tools to biological applications of information theory, along with a Black–Scholes model invocation of the Data Rate Theorem which links information and control theories. The focus is on statistical mechanics and other models that explore pathological phase transitions — driven by changes in available rates of mitochondrial free energy — in physiological functions, a cutting-edge topic in the study of chronic disease. One of the key focuses is Alzheimer's disease — a relatively simple canonical example.

Contents:
  • Mathematical Preliminaries
  • A Symmetry-Breaking Model
  • A Data Rate Theorem Model
  • A Mutual Information Model
  • A Fragment Size Model
  • Extending the Perspective
  • Embodiment and Environment
  • Chronic Inflammation
  • What is to be Done?
  • Mathematical Appendix

Readership: Graduate students and researchers interested in biological applications of information theory.
Key Features:
  • Significantly extends current thinking on Alzheimer's and related chronic diseases
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Non-FictionMathematicsApplied MathematicsMathematical ModellingScienceBiology, Life SciencesLife Sciences in GeneralNeurosciences

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