Exposure-Response Modeling

Methods and Practical Implementation

By: Jixian Wang

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eText | 17 July 2015 | Edition Number 1

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Discover the Latest Statistical Approaches for Modeling Exposure-Response Relationships. Written by an applied statistician with extensive practical experience in drug development, this book explores a wide range of topics in exposure-response modeling, from traditional PKPD modeling to other areas in drug development and beyond. It incorporates numerous examples and software programs for implementing novel methods. The book emphasizes dose adjustment and treatment adaptation based on dynamic exposure-response models, illustrates how to apply causal inference to exposure-response modeling in pharmacometrics and epidemiology, and links exposure-response modeling to clinical decision making through model-based decision analysis.