SECTION I : Evidence-based Methods in Dementia.Introduction.
Finding the evidence.
Critical Appraisal.
Evidence-based Etiology and Harm.
Evidence-based Diagnosis.
Evidence-based Prognosis.
Evidence-based Interventions.
Evidence-based Systematic Reviews and Meta-analyses.
Evidence-based Guidelines.
Evidence-based Economic Evaluation.
Accessing and Using the Best Evidence Efficiently in Dementia.
Evidence-based Audit: Evaluating Implementation.
SECTION II : Diagnosis.
Introduction Practice Guidelines.
Reaching a Diagnosis of Dementia.
Reaching a Diagnosis of Dementia Subtype Conclusions.
SECTION III : Background Facts.
Historical Evolution of the Concept of Dementia: a Systematic Review From 2000 BC to 2000 AD.
Alzheimer's Disease.
Vascular Dementia.
Lewy Body Dementia.
Frontotemporal Lobar Atrophies: The Pick Complex.
Other Important Dementias.
Reversible or Arrestable Dementias.
Mild Cognitive Impairment.
SECTION IV: Overview of Treatment and Management.
Aims of Treatment.
Criteria for Clinical Decisions.
Clinical Decisions in Practice.
Delivering an Integrated Treatment Plan.
What is the Evidence that a Dementia Treatment Works?.
Non-pharmacological Techniques.
Drugs in Development and Experimental Approaches.
SECTION V: Therapies for Cognitive Symptoms, Disease Modification and Prevention.
Introduction to Specific Therapies for Cognitive Symptoms or Modifying Disease Prognosis.
Treatment of Alzheimer's Disease (With or Without Cerebrovascular disease).
Treatment of Vascular Dementia.
Treatment of Lewy Body Dementia.
Treatment of Reversible or Arrestable Dementias.
Treatment of Age-associated Memory Impairment.
Prevention of Dementia.
SECTION VI: Treating Non-cognitive Problems.
VI.A: A Problem-oriented Approach to Common Psychiatric Problems.
Introduction.
Classes of Psychotropics - Overview of Evidence from Clinical Trials.
Problems.
Summary, Practical Recommendations and Opinions.
VI.B: A Problem-oriented Approach to Common Medical Problems.
Common Medical Problems.
SECTION VII: Social, Ethical and Health Services Issues.
Social and Ethical Issues.
Driving.
Care-giver Interventions.
Genetic Counseling.
Nursing Home Care for Patients with Dementia.
Organisation of Care.
Memory Clinics - a Guide to Implementation and Evaluation.
Health Economics.
APPENDIX 1: Diagnostic Criteria for Common Dementias.
APPENDIX 2: Dementia Rating Scales.
APPENDIX 3: National Alzheimer's Disease and Dementia Associations and Societies.
