
Comparative Pharmacokinetics
Principles, Techniques and Applications
By: Jim E. Riviere (Editor)
eBook | 14 January 2011 | Edition Number 2
At a Glance
432 Pages
eBook
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Now in a revised edition, Comparative Pharmacokinetics: Principles, Techniques, and Applications presents the principles and techniques of comparative and veterinary pharmacokinetics in a detailed yet practical manner. Developed as a tool for ensuring that pharmacokinetics studies are properly designed and correctly interpreted, the book provides complete coverage of the conceptual basis of pharmacokinetics as used for quantifying biological processes from the perspectives of physiology and medicine. New chapters have been added on quantitative structure permeability relationships and bioequivalence, and a number of existing chapters have been significantly revised and expanded to provide a current resource for veterinary and comparative pharmacokinetics.
Industry Reviews
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Preface.
1 Introduction.
2 Principles of Drug Movement in the Body.
3 Quantitative Structure-Permeability Relationships (Xin-Rui Xia).
4 Absorption.
5 Distribution (with Jennifer Buur).
6 Renal Elimination.
7 Hepatic Biotransformation and Biliary Excretion (Ronald Baynes).
8 Compartmental Models.
9 Noncompartmental Models.
10 Nonlinear Models.
11 Physiological Models (Teresa Leavens).
12 Dosage Regimens.
13 Simultaneous Pharmacokinetic-Pharmacodynamic Modeling (Pierre-Louis Toutain).
14 Study Design and Data Analysis. (Jason Chittenden).
15 Bioequivalence Studies (Marilyn Martinez).
16 Population Pharmacokinetic Models (Jason Chittenden).
17 Dosage Adjustments in Disease States (Jennifer Davis).
18 Interspecies Extrapolations.
19 Tissue Residues and Withdrawal Times (Sharon Mason).
Index.
ISBN: 9780470959886
ISBN-10: 0470959886
Published: 14th January 2011
Format: ePUB
Language: English
Number of Pages: 432
Audience: Professional and Scholarly
Publisher: Wiley
Country of Publication: US
Edition Number: 2
























