By: K. E. Healy (Editor), David J. Mooney (Editor), Yoshito Ikada (Editor), A. G. Mikos (Editor), R. C. Thomson (Editor)

Hardcover

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The primary goal of tissue engineering is to create natural living tissue to restore normal mechanical, metabolic or aesthetic function to an individual. The appropriate design of biomaterials, however, plays a key role in regulating cell behavior and tissue response, and is a key part of tissue regeneration strategy. Consequently, the realm of tissue engineering has come to encompass many materials-based disciplines. This book focuses on the modification and characterization of both natural and synthetic materials to alter the human body's regenerative response. More specifically, the volume consists of three sections. The design, preclinical and clinical evaluation of biomaterials and biomaterial-cell constructs aimed at functional tissue reconstruction is the primary focus of Part I. Control of cell interactions by tailoring biomaterial chemistry or surface properties is highlighted in Part II. Part III features orthopedic applications of cell interactive biomaterials.

Preface
A New Approach to Cartilage Tissue Engineering Using Human Dermal Fibroblasts Seeded on Three-Dimensional Polymer Scaffolds	p. 3
Investigating Islet Immunoisolation Parameters Using Microfabricated Membranes	p. 7
Comparison of Release Profiles of Various Growth Factors From Biodegradable Carriers	p. 13
A Model for Oxygen Transport in Microencapsulated Islets	p. 19
Modification of Fibroin Film With a Chimera Fibroin Fragment for Improvement of Cell Adhesion	p. 27
Positron Annihilation Lifetime Measurements in Collagen Biopolymer	p. 33
PEG Cross-Linked Alginate Hydrogels With Controlled Mechanical Properties	p. 37
"Construction of Biomimetic Environments With a Synthetic Peptide Analogue of Collagen	p. 43
Materials Designed to Control and Examine the Function of Single Cells	p. 55
Neuronal Outgrowth Guidance on Patterned Organic Films	p. 59
Development of a Flexible Cell Targeting System Based on Silica Nanoparticles	p. 65
Tailoring Polymer Surfaces for Controlled Cell Behavior	p. 73
Cross-Linking Characteristics of an Injectable Poly(propylene fumarate)/[beta]-Tricalcium Phosphate Paste and Mechanical Properties of the Cross-Linked Composite for Use as a Biodegradable Bone Cement	p. 87
Osteocompatibility of Photopolymerizable Anhydride Networks	p. 93
Biomolecular Surface Engineering of Materials for Controlling Bone Cell Adhesion and Spreading	p. 99
Proliferation of Human Osteoblastic Cells and Synthesis of Extracellular Bone Matrix on Biomaterials	p. 105
Surface Interaction of Inflammatory Species With Titanium and Titanium Oxide	p. 111
Author Index	p. 117
Subject Index	p. 119
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9781558994362
ISBN-10: 155899436X
Series: MRS Proceedings
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 119
Published: 10th November 1998
Publisher: Materials Research Society
Weight (kg): 1.0