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Published: 15th December 2010Voltage Gated Calcium Channels is the first comprehensive book in the calcium channel field, encompassing over thirty years of progress towards our understanding of calcium channel structure, function, regulation, physiology, pharmacology, and genetics. This book balances contributions from many of the leading authorities in the calcium channel field with fresh perspectives from risings stars in the area, taking into account the most recent literature and concepts. This is the only all-encompassing calcium channel book currently available, and is an essential resource for academic researchers at all levels in the areas neuroscience, biophysics, and cardiovascular sciences, as well as to researchers in the drug discovery area.
| Ca[superscript 2+] chemistry, storage and transport in biologic systems : an overview | p. 1 |
| Monitoring intracellular Ca[superscript 2+] in brain slices with fluorescent indicators | p. 12 |
| A brief history of calcium channel discovery | p. 27 |
| Biochemical studies of voltage-gated Ca[superscript 2+] channels | p. 48 |
| Molecular properties of voltage-gated calcium channels | p. 61 |
| Role of [beta] subunits in voltage-gated calcium channel functions | p. 95 |
| Distribution and targeting mechanisms of voltage activated Ca[superscript 2+] channels | p. 113 |
| The calcium channel and the transmitter release site | p. 141 |
| Determinants of G protein inhibition of presynaptic calcium channels | p. 154 |
| Phosphorylation-dependent regulation of voltage-gated Ca[superscript 2+] channels | p. 168 |
| Ca[superscript 2+]-dependent modulation of voltage-gated Ca[superscript 2+] channels | p. 183 |
| Voltage-dependent inactivation of voltage gated calcium channels | p. 194 |
| Selective permeability of voltage-gated calcium channels | p. 205 |
| The run-down phenomenon of Ca[superscript 2+] channels | p. 219 |
| Calcium channels as therapeutic targets | p. 231 |
| Calcium channelopathies | p. 240 |
| The molecular basis of Ca[superscript 2+] antagonist drug action-recent developments | p. 262 |
| Calcium channel block and inactivation : insights from structure-activity studies | p. 281 |
| Block of voltage-gated calcium channels by peptide toxins | p. 294 |
| Calcium channels in the heart | p. 309 |
| Post-genomic insights into T-type calcium channel functions in neurons | p. 326 |
| Voltage-gated Ca[superscript 2+] channels of the vertebrate retina : from the genetics of blindness to encoding the visual world | p. 334 |
| Exploring the function and pharmacotherapeutic of potential voltage-gated Ca[superscript 2+] channels with gene-knockout models | p. 346 |
| Table of Contents provided by Blackwell. All Rights Reserved. |
ISBN: 9780306478406
ISBN-10: 0306478404
Series: Molecular Biology Intelligence Unit
Audience:
Professional
Format:
Hardcover
Language:
English
Number Of Pages: 378
Published: 1st February 2005
Publisher: Springer Science+Business Media
Country of Publication: US
Dimensions (cm): 22.9 x 15.2
x 2.54
Weight (kg): 0.83
