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Vascular Morphogenesis : In Vivo, In Vitro, In Mente - Vladimir Mironov

Vascular Morphogenesis

In Vivo, In Vitro, In Mente

By: Vladimir Mironov (Editor), Charles Little (Editor), Helen Sage (Editor)

Hardcover Published: 29th September 1998
ISBN: 9780817639204
Number Of Pages: 265

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The overall scope of this new series will be to evolve an understanding of the genetic basis of (1) how early mesoderm commits to cells of a heart lineage that progressively and irreversibly assemble into a segmented, primary heart tube that can be remodeled into a four-chambered organ, and (2) how blood vessels are derived and assembled both in the heart and in the body. Our central aim is to establish a four-dimensional, spatiotemporal foundation for the heart and blood vessels that can be genetically dissected for function and mechanism. Since Robert DeHaan's seminal chapter "Morphogenesis of the Vertebrate Heart" pubĀ­ lished in Organogenesis (Holt Reinhart & Winston, NY) in 1965, there have been surprisingly few books devoted to the subject of cardiovascular morphogenesis, despite the enormous growth of interest that occurred nationally and internationally. Most writings on the subject have been scholĀ­ arly compilations of the proceedings of major national or international symposia or multiauthored volumes, often without a specific theme. What is missing are the unifying concepts that can make sense out of a burgeoning database of facts. The Editorial Board of this new series believes the time has come for a book series dedicated to cardiovascular morphogenesis that will serve not only as an important archival and didactic reference source for those who have recently come into the field but also as a guide to the evolution of a field that is clearly coming of age.

List of Contributors
Series Preface
Vascular Morphogenesis In Vivo
Introduction: Understanding Blood Vessel Assembly in the Embyrop. 1
The Morphogenesis of Primordial Vascular Networksp. 3
Angiogenesis and Lymphangiogenesis: Analogous Mechanisms and Homologous Growth Factorsp. 21
Ontogeny of the Endothelial Network Analyzed in the Avian Modelp. 35
Methodology for the Study of Vascular Morphogenesis In Vivop. 51
Growth Factors in Vascular Morphogenesis: Insights from Gene Knockout Studies in Micep. 65
Vascular Morphogenesis In Vitro
Introduction: Regulation of Vascular Morphogenesisp. 73
Three-Dimensional In Vitro Assay of Endothelial Cell Invasion and Capillary Tube Morphogenesisp. 79
The Rat Aorta Model of Angiogenesis and Its Applicationsp. 111
In Vitro Coculture Models to Study Vessel Formation and Functionp. 131
Vascular Morphogenesis in Mente
Introduction: Toward the Theoretical Biology of Vascular Morphogenesisp. 141
Models for the Formation of Netlike Structuresp. 147
A Mechanical Theory of In Vitro Vascular Network Formationp. 173
Blood Vessel Growth: Mathematical Analysis and Computer Simulation Fractality, and Optimalityp. 189
Mathematical Modeling of Tumor-Induced Angiogenesisp. 205
Is the Fractal Nature of Intraorgan Spatial Flow Distributions Based on Vascular Network Growth or on Local Metabolic Needs?p. 241
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9780817639204
ISBN-10: 0817639209
Series: Cardiovascular Molecular Morphogenesis
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 265
Published: 29th September 1998
Country of Publication: US
Dimensions (cm): 23.5 x 15.5  x 1.27
Weight (kg): 1.27