Uses of Immobilized Biological Compounds : Proceedings of the NATO Advanced Research Workshop on Uses of Immobilized Biological Compounds for Detection, Medical, Food and Environmental Analysis, Brixen, Italy, May 9-14, 1993

By: George G. Guilbault (Editor), Marco Mascini (Editor)

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In Uses of Immobilized Biological Compounds the reader will find a comprehensive survey of the field written by acknowledged experts who met in Brixen, Italy, between May 9 and 14, 1993 for a NATO Advanced Research Workshop devoted to the topic. The resulting volume presents a critical review of the latest results in the area and sets guidelines for future research. The 53 reports presented here cover: (A) General Aspects of Immobilizing Biological Compounds; (B) Medical, Clinical and Pharmaceutical Applications; (C) Electrochemical Biosensors; (E) Defense Applications; (F) Immunosensors and Receptors; (G) Food, Environmental, Clinical and Analytical Applications; and (H) Biotechnology and Marketing. In short, all aspects of the area are presented, in a compact format which will appeal to undergraduates, technicians, and professional scientists in the food, clinical, environmental, pharmaceutical and industrial fields.

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Non-Fiction Engineering & Technology Electronics & Communications Engineering Electronics Engineering Electronic Devices & Materials Science Chemistry Organic Chemistry Industrial Chemistry & Manufacturing Technologies Industrial Chemistry Plastics & Polymers Technology Biochemical Engineering

Biotechnology Physical Chemistry Medicine Pre-Clinical Medicine & Basic Sciences Biology, Life Sciences Zoology & Animal Sciences

Preface
List of Contributors
Immobilization of Biological Species on Bilayer Lipid Membranes	p. 1
Polymeric Environments for Proteins and Whole Cells in Molecular Sensors	p. 11
Use of Red Blood Cells (RBC) as Carriers of Bioactive Compounds	p. 23
Theoretical and Experimental Aspects for Improvement of Electrochemical Biosensors by Various Kinds of Immobilization	p. 35
Development and Characterization of Polymeric Biomaterials for Bioactive Agent Immobilization	p. 47
Two-Dimensional (Glyco)protein Crystals as an Immobilization Matrix for Functional Molecules	p. 57
Application of Graphite-Epoxy Composites in the Construction of Electrochemical Sensors and Biosensors	p. 67
Novel PHEMA Membranes for Potential Bioelectrode Use	p. 81
Immobilization of Cell Cycle Specific Drug DFMO for Chemotherapy	p. 91
Use of Immobilized Biological Compounds in Drug Analysis	p. 101
In-Vivo Monitoring with Microdialysis Probe	p. 115
Immobilised Catalase and Hydrogen Peroxide. A Novel Contact Lens Disinfection System	p. 123
Ex-Vivo Sensors; Microencapsulation of Enzyme Layer in Biosensors	p. 131
Clinical Application of Biosensing with Amperometric Detection of Ammonia-Nitrogen	p. 141
Therapeutic Potential of Immobilized Enzymes	p. 151
Optimization of Membranes with Glucose Oxidase for Glucose Determination Using Oxygen Electrode	p. 161
Multienzyme Biosensors. Coupled Enzyme Reactions and Enzyme Activation	p. 171
Three Different Approaches for Preparing GLOD and GLDH Reactors. Application for the Assay of Glutamates in Real Samples Using a FIA System	p. 181
Enzyme Immobilization on Chitin and Chitosan for Construction of Enzymatic Sensors	p. 191
Electrochemical Biosensors	p. 201
Novel Approaches to the Development of Mediated Biosensors and Enzyme Assay	p. 211
Poly(Amphiphilic Pyrrole)-Enzyme Electrode: A New Approach for Biosensor Construction	p. 231
Effect of Organic Solvents on the Behaviour of a Glucose Oxidase-Based Biosensor	p. 245
Organic-Phase Biosensors	p. 255
Modified Enzyme Electrodes	p. 263
Can New Biosensors be Deduced from Sensing in Biology?	p. 271
Microbial Sensors and Microbiosensors	p. 281
Stimulus-Response Measurements on Protein Containing Membranes Deposited on an ISFET Surface	p. 289
Micro Sensors in Bioelectroanalysis	p. 309
Surface Characteristics of Chemical Sensors	p. 325
Optrodes for Measuring Enzyme Activity and Inhibition	p. 335
Luminescence Detection of Biological Reactions	p. 345
Progress in Fiber-Optic Based Biosensors at the United States Naval Research Laboratory	p. 351
Immobilized Biological Compounds in Defense Applications	p. 359
Biosensors in the Detection of Biological Agents	p. 369
Biosensors for Toxins and Bacteria	p. 377
Reusable Fiber Optic Biosensors for Detection of Drugs and Toxicants	p. 387
The Biosensor Technology Program at NIST	p. 397
FIA Immunoassays with Electrochemical and Optical Detection	p. 415
Immunoassay Devices for Extra-Laboratory Measurements of Toxic Chemicals Based on Capillary Migration and Liposome Amplification	p. 421
Direct Immunoassays: Limitations on the Physical Principles and on the Technology State of the Art	p. 433
Comparison of Different Solid Phases for an ELISA Based Determination of Aflatoxin B	p. 443
Polystyrene and Poly(styrene/acrolein) Latexes with Immobilized Proteins as a Basis of the Diagnostic Agglutination Test	p. 453
An Integrated Optical Immunosensor	p. 463
Immobilized Biological Compounds in Food Analysis	p. 471
Immobilized Biomolecules for Detection of Environmental Pollutants	p. 477
Enzyme Inhibition Sensor for Organophosphorus Pesticides Analysis	p. 489
Biosensors for Electrochemical Non Invasive Analysis	p. 501
Flow Through Biosensors in Clinical Analysis	p. 515
Flow Injection Analysis: A Complementary or Alternative Concept to Biosensors	p. 527
Heat Sensitive Biosensors	p. 541
The Market for Biosensors. The Strengths and the Competition	p. 549
Report on Biosensor Technology in Europe	p. 559
Author Index	p. 567
Subject Index	p. 571
Table of Contents provided by Blackwell. All Rights Reserved.

Uses of Immobilized Biological Compounds : Proceedings of the NATO Advanced Research Workshop on Uses of Immobilized Biological Compounds for Detection, Medical, Food and Environmental Analysis, Brixen, Italy, May 9-14, 1993

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