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Understanding DNA : The Molecule and How it Works - Andrew Travers

Understanding DNA

The Molecule and How it Works

Hardcover

Published: 13th March 2004
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The functional properties of any molecule are directly related to, and affected by, its structure. This is especially true for DNA, the molecular that carries the code for all life on earth.
The third edition of Understanding DNA has been entirely revised and updated, and expanded to cover new advances in our understanding. It explains, step by step, how DNA forms specific structures, the nature of these structures and how they fundamentally affect the biological processes of transcription and replication.
Written in a clear, concise and lively fashion, Understanding DNA is essential reading for all molecular biology, biochemistry and genetics students, to newcomers to the field from other areas such as chemistry or physics, and even for seasoned researchers, who really want to understand DNA.
* Describes the basic units of DNA and how these form the double helix, and the various types of DNA double helix
* Outlines the methods used to study DNA structure
* Contains over 130 illustrations, some in full color, as well as exercises and further readings to stimulate student comprehension

Praise for previous editions: "Stylish...beautifully crafted, with a logical step-by-step approach to the subject. A book from which the advanced undergraduate will benefit and which will also generate a refreshing perspective for experts" -NATURE

"Understanding DNA is a great book that will surely prove to be a valuable teaching tool." -THE BIOCHEMIST

"A systematic and comprehensive analysis of the structure of DNA from a wonderfully fresh perspective." -TRENDS IN GENETICS

Prefacep. xi
An Introduction to Molecular Biology for Non-Scientistsp. 1
Why a Helix?p. 18
Different Kinds of Double Helixp. 39
Twisting and Curvingp. 64
Curving in Three Dimensionsp. 94
DNA Supercoilingp. 116
The Assembly of DNA into Chromosomesp. 139
Specific DNA-Protein Interactionsp. 173
Methods Used to Study the Structure of DNAp. 203
DNA in Disease, Diagnostics, and Medicinep. 235
Cytosine Methylation and DNA Epigeneticsp. 270
Postscriptp. 295
Notes on the Derivation of Some Technical Termsp. 299
The Chemical Theory of Base-stacking Interactions in DNAp. 301
How to modify Gene Expression Using Anti-sense Oligonucleotides, Ribozymes or Small Interfering-RNAp. 312
Answers to Selected Exercisesp. 323
Indexp. 327
Table of Contents provided by Rittenhouse. All Rights Reserved.

ISBN: 9780121550899
ISBN-10: 0121550893
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 352
Published: 13th March 2004
Publisher: Elsevier Science Publishing Co Inc
Country of Publication: US
Dimensions (cm): 24.4 x 17.1  x 1.91
Weight (kg): 0.86
Edition Number: 3
Edition Type: Revised