| Preface | |
| Contributors | |
| Reflecting Forward: Gastroenterology in the New Millennium | p. 3 |
| Pathophysiology of and New Treatment for Ulcerative Colitis | p. 15 |
| New Target of Gastroenterology: Overcoming Life Style-Related Diseases | p. 27 |
| Examination of Cytotoxic T Lymphocyte-Mediated Apoptosis Pathway in Peptic Ulcer Formation with or without H. pylori Infection | p. 35 |
| Epidermal Growth Factor Inhibits Helicobacter pylori Lipopolysaccharide-Induced Apoptosis of Primary Cultures of Gastric Pit Cells | p. 43 |
| Impaired Sensitivity to Fas-Induced Apoptosis of Lymphocytes in Ulcerative Colitis Lesions | p. 47 |
| Tumor Necrosis Factor [alpha]-Induced Hepatic Apoptosis and Hepatocyte Sensitization | p. 53 |
| Molecular Mechanisms of D-Galactosamine/Lipopolysaccharide-Induced Fulminant Hepatic Failure in Mice and the Effects of Therapeutic Agents | p. 59 |
| Ethanol-Induced Apoptosis Mediated by Mitochondrial Permeability Transition in Primary Cultured Sinusoidal Endothelial Cells | p. 63 |
| Therapeutic Strategies for Hepatocellular Carcinoma Based on Analyses for Resistance to Apoptosis Mediated by Activation of Intracellular Signal Pathways | p. 66 |
| Expression of Apoptosis-Related Factors in Human Pancreatic Duct Cell Carcinoma and Intraductal Papillary-Mucinous Tumor | p. 71 |
| Effect of Exogenous and Endogenous Nitric Oxide on Endothelial Permeability Induced by Oxidants In Vitro | p. 79 |
| Gastric Carcinoma and Helicobacter pylori Infection: Role of Nitric Oxide and Inflammatory Cytokines in Gastric Carcinogenesis | p. 82 |
| Does Cyclooxygenase-2 Down-Regulate Gastric Inflammation? | p. 86 |
| Regulation of Mucin Synthesis by Neuronal Nitric Oxide Synthase in Gastric Pit Cells | p. 90 |
| Role of Nitric Oxide and Capsaicin-Sensitive Sensory Nerves in Gastric Receptive Relaxation and Adaptive Relaxation in Isolated Stomachs of Guinea Pigs | p. 95 |
| Role of Inducible Nitric Oxide Synthase in Murine Colitis | p. 99 |
| Role of Nitric Oxide in the Progression of Severe Acute Pancreatitis | p. 103 |
| Role of Nitric Oxide in the Progression of Acute Pancreatitis | p. 106 |
| Protective Effect of Nitric Oxide on Acute Liver Failure in Rats | p. 112 |
| Regulatory Mechanism of Cationic Amino Acid Transporters in Hepatic Sinusoidal Ito Cells | p. 115 |
| Novel NADPH Oxidase, Moxl, Expressed in Cultured Gastric Pit Cells: Modulation of NF-[kappa]B Activation | p. 123 |
| Role of PPAR[gamma] in the Growth and Differentiation of Gastric and Colorectal Cancers | p. 128 |
| PPAR[gamma] Ligand and Induction of Growth Arrest in Pancreatic Cancer Cells | p. 132 |
| Role of [beta]-Catenin During Early Colorectal and Hepatic Carcinogenesis | p. 138 |
| Growth Inhibition of Hepatoma Cells by Type 1 Interferons: Modification by Mutations in the Interferon Regulatory Factor-1 Gene | p. 142 |
| Growth Inhibition of Pancreatic Cancer Cell Lines by Ligand Activation of Nuclear Hormone Receptors Through Up-Expression of WAF1/CIP1/p21 | p. 147 |
| Immunopathological Features of Granuloma Formation in the Intestinal Mucosa of Patients with Crohn's Disease | p. 155 |
| Helicobacter pylori and N-Methyl-N'-nitro-N-nitrosoguanidine Induction of Dendritic Cell Infiltration of the Pyloric Mucosa of Mongolian Gerbils | p. 160 |
| Cytotoxic Effect of Bone Marrow-Derived Dendritic Cells | p. 167 |
| Autoimmune Mechanisms of Cancer-Associated Paraneoplastic Syndromes: A Review | p. 171 |
| Antitumor Activity Against Gastrointestinal and Hepatocellular Carcinoma Induced by Immunization with Fusion of Dendritic and Carcinoma Cells in Mice | p. 175 |
| Essential Role for Interleukin-6 in the Pathogenesis of Crohn's Disease | p. 173 |
| Activation of Nuclear Factor [kappa]B in Dextran Sulfate Sodium-Induced Colitis in Mice and Their Inhibition by Phenyl N-tert-Butylnitrone | p. 187 |
| Essential Roles for Th2-Type Responses in Chronic Intestinal Inflammation | p. 193 |
| Induction of Colitis and Exocrinopathy in Nude Mice Induced by Immunocompetent Cell Transfer from Murine Retrovirus-Infected Mice | p. 197 |
| Potential Role of Mucosal Addressin Cell Adhesion Molecule-1 in Inflammatory Bowel Diseases | p. 201 |
| Anti-Saccharmomyces cerevisiae Antibody in Inflammatory Bowel Disease | p. 205 |
| Reactive Oxygen Species and Colonic Epithelial Cell Apoptosis in Ulcerative Colitis | p. 208 |
| Effect of Antiulcer Drugs for Treatment of Nonsteroidal Antiinflammatory Drug-Induced Ulcers | p. 215 |
| Role of Intravascular Neutrophils in the Pathogenesis of Aspirin-Induced Gastric Mucosal Injury | p. 219 |
| Mucin Secretion Evoked by Prostaglandin E[subscript 2] in Guinea Pig Antral Mucous Cells: Role of EP1/EP4 Receptors | p. 224 |
| Effects of Indomethacin and NS-398 on Acid-Induced E-Cadherin Surface Expression in Rat Gastric Epithelial Cells | p. 229 |
| Roles of Reactive Nitrogen Species in Helicobacter-Related Carcinogenesis | p. 233 |
| Interaction Between Helicobacter pylori Infection and NSAID Use | p. 237 |
| Interrelations of Nonsteroidal Antiinflammatory Drugs, H. pylori Infection, and Gastric Damage | p. 242 |
| Microvascular Leukocyte Activation and Apoptosis in Helicobacter pylori-Colonized Gastric Mucosa | p. 249 |
| Alteration of Gastric Microcirculatory Achitecture During Healing of Acetic Acid-Induced Ulcer and Helicobacter pylori Infection | p. 257 |
| Cyclooxygenase and Colon Cancer | p. 263 |
| Contribution of Colon Cancer Cells to Mesenchymal Cells in the Formation of Hepatic Metastasis | p. 267 |
| Hepatic Microcirculation in Massive Liver Necrosis and Liver Regeneration | p. 272 |
| Prevention of Hepatic Ischemia/Reperfusion Injury by Microcirculatory Regulation: Application to Liver Transplantation | p. 277 |
| Genetic Manipulation of Sinusoidal Endothelial Cells | p. 283 |
| Controlling Tumor Microenvironment by the Antiangiogenesis Strategy | p. 287 |
| Pancreatic Blood Flow in Chronic Alcoholic Pancreatitis | p. 290 |
| The Role of Hepatic Oval Cells in Hepatic Regeneration: Possible Clinical Applications | p. 297 |
| Hepatoma-Derived Growth Factor: Involvement in Liver Development and Regeneration | p. 302 |
| Tumor Necrosis Factor and Liver Regeneration | p. 306 |
| Heparin-Binding EGF-Like Growth Factor: Hepatotrophic Factor in Liver Regeneration | p. 312 |
| Effects of Growth Stimulatory and Inhibitory Factors on Signal Transduction of Cultured Rat Hepatocyte and the Regulation of Cyclin D1 Transcription | p. 317 |
| Significance of the Relation Between Hepatocyte Growth Factor and Transforming Growth Factor-[alpha] in Hepatocyte Proliferation | p. 321 |
| Transcriptional Regulation of Type I Collagen Gene Expression by Transforming Growth Factor-[beta] and Smad Proteins | p. 327 |
| Clinical Usefulness of Plasma MMP-9 Assay Compared with the Plasma MMP-2 Assay in Patients with Chronic Liver Disease | p. 331 |
| Molecular Mechanisms of Matrix Metalloproteinase-1 Gene Expression in Hepatic Stellate Cells | p. 336 |
| Molecular Analysis of Stellate Cells Activation by Proteomics | p. 340 |
| Tissue Inhibitor of Metalloproteinase-1: Strong Promotion of Liver Fibrosis Development in the Transgenic Mouse Model | p. 344 |
| Antioxidant and Antiapoptotic Activities of a Tissue-Specific Selective Estrogen Receptor Modulator, Idoxifene, in Rat Fibrotic Liver and Cultured Rat Hepatocytes | p. 350 |
| Blockade of TGF[beta] Signaling: Prevention of Fibrosis/Dysfunction and Enhancement of Hepatocyte Regeneration in Injured Liver | p. 356 |
| Protease Inhibitors: Suppression of Activation of Hepatic Stellate Cells by Inhibiting TGF[beta] Generation | p. 361 |
| Plasma Transforming Growth Factor-[beta]1: A Useful Marker for Hepatic Fibrosis in Chronic Hepatitis C | p. 364 |
| Key Word Index | p. 367 |
| Table of Contents provided by Blackwell. All Rights Reserved. |
