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Toxicology : A Case-Oriented Approach - John Joseph Fenton


A Case-Oriented Approach

Hardcover Published: 10th October 2001
ISBN: 9780849303715
Number Of Pages: 600

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Intriguing anecdotal pedagogy, like the alleged arsenical poisonings of Napoleon and President Taylor and the probable mercury overdose of Isaac Newton, is one of the things that set Toxicology: A Case-Oriented Approach apart from other toxicology texts. Based on an undergraduate-graduate combined toxicology course at West Chester University, this innovative text captures readers' interest by combining modern case studies, historical cases, and hundreds of illustrations and tables. Each chapter presents several case scenarios that involve the reader with questions about diagnosis, testing methods, treatment, and other pertinent information.
In an easy-to-read style, this book covers the major organ systems and reviews the effects of toxins in each system. Most contemporary books are almost entirely clinical or entirely analytical. Toxicology: A Case-Oriented Approach treats each area extensively to benefit students and professionals who need to know aspects of both. It describes diagnosis and treatment of each specific poisonous exposure and discusses chemical basis and the laboratory testing of toxins. This dual perspective, coupled with the book's interesting narrative approach, lets readers quickly absorb the information they need to understand toxicology in the laboratory and in the Emergency Department.

Industry Reviews

"brings together toxicology, clinical medicine and bioanalytical sciences in an easily understood narrative to help ensure a greater cross-disciplinary undestanding to support the highest standard of poisoned patient treatmenta useful reference book for undergraduates; it will be especially helpful for post-graduates and physician preparing for professional qualifications. The book could also be of interest to the clinical toxicologists and academic teacher." -Peter H. Bach, Celltech Research and Development "For 10 years I taught a graduate course, 'Toxicology and Drug Analysis', and a problem I faced was the lack of a suitable textbook. This problem appears to be solved with the publication of Toxicology: A Case-Oriented Approach. Sixty-three interesting and pertinent case studies are woven through this book, representing a new approach to teaching this often confusing an complicated subject... In short, this book is an excellent resource for teachers, clinical and forensic toxicologists, and physicians practicing emergency medicine." -James F. Wesley, Monroe County Crime Laboratory "a fun book to read and easily involves the reader with a casual narrative style that is great for student learning and rapidly relating information to the emergency room, laboratory, and mechanisms of present-day toxicology. The 35-page index is a masterpiece an intriguing and innovative book that holds the reader's attention with unexpected ease. The information is accurate, it is clearly and practically presented, and the reader is left with the nagging feeling that 'This is exciting, and I want to learn more!' What greater tribute can an author and an instructor receive than to be appreciated for agreat presentation of a stimulating and dynamic discipline." - Veterinary and Human Toxicology, December 2002 "written in an easily understood and enjoyable mannerThis book is a unique and valuable attempt to acquaint two different disciplines that commonly depend on each other. Clearly they would be more effective if they had a better understanding of the other's problems. It could be used as a textbook in introductory toxicology courses or adjunctive reading for basic toxicologists. Physicians can learn valuable insights into interpretation of laboratory investigations of their patients. The quality of either discipline's conclusions would be improved by this shared knowledge." - Sheldon L. Wagner, M.D. in Doody's Notes "A major strength of this book is its reliance on case studies to stimulate the interest of the reader. These case studies have been carefully selected for their abilities to teach important principles related to toxicology. Also, Fenton includes many interesting anecdotes related to the history of toxicology. This book is thorough and comprehensive in its coverage of the toxicology subject and manages to maintain reader interest through hands-on exercises placed throughout." - R. Saferstein, Widener University, in CHOICE

History of Toxicologyp. 1
Measuring Toxicityp. 13
Therapyp. 25
The Role of the Laboratory in Diagnosis and Treatment of Poisoningp. 41
Introductory Toxicokineticsp. 51
Biotransformationp. 69
Hepatic Toxicityp. 85
Renal Toxicologyp. 99
Cardiac Toxicityp. 111
Neurological Toxicityp. 129
Pulmonary Toxicologyp. 163
Drug Testing: Screeningp. 179
Confirmatory Tests in Toxicologyp. 195
Metal Analysis (Assay of Toxic Metals)p. 221
Alcoholsp. 231
Toxic Gasesp. 257
Insecticidesp. 283
Metalsp. 303
Over-the-Counter Analgesicsp. 335
Drugs of Abusep. 359
Sedatives and Hypnoticsp. 403
Stimulantsp. 429
Anticholinergic Drugsp. 443
Psychedelic Drugsp. 469
Plantsp. 487
Snake Venomsp. 519
Indexp. 537
Table of Contents provided by Syndetics. All Rights Reserved.

ISBN: 9780849303715
ISBN-10: 0849303710
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 600
Published: 10th October 2001
Publisher: Taylor & Francis Inc
Country of Publication: US
Dimensions (cm): 23.5 x 15.88  x 3.81
Weight (kg): 0.93
Edition Number: 1