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Toward Replacement Parts for the Brain : Implantable Biomimetic Electronics as Neural Prostheses - Theodore W. Berger

Toward Replacement Parts for the Brain

Implantable Biomimetic Electronics as Neural Prostheses

By: Theodore W. Berger (Editor), Dennis L. Glanzman (Editor)

Hardcover Published: 1st June 2005
ISBN: 9780262025775
Number Of Pages: 480
For Ages: 18+ years old

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The continuing development of implantable neural prostheses signals a new era in bioengineering and neuroscience research. This collection of essays outlines current advances in research on the intracranial implantation of devices that can communicate with the brain in order to restore sensory, motor, or cognitive functions. The contributors explore the creation of biologically realistic mathematical models of brain function, the production of microchips that incorporate those models, and the integration of microchip and brain function through neuron-silicon interfaces. Recent developments in understanding the computational and cognitive properties of the brain and rapid advances in biomedical and computer engineering both contribute to this cutting-edge research.The book first examines the development of sensory system prostheses -- cochlear, retinal, and visual implants -- as the best foundation for considering the extension of neural prostheses to the central brain region. The book then turns to the complexity of neural representations, offering, among other approaches to the topic, one of the few existing theoretical frameworks for modeling the hierarchical organization of neural systems. Next, it examines the challenges of designing and controlling the interface between neurons and silicon, considering the necessity for bidirectional communication and for multiyear duration of the implant. Finally, the book looks at hardware implementations and explores possible ways to achieve the complexity of neural function in hardware, including the use of VLSI and photonic technologies.

"An overview of vigorous ongoing efforts to lay the foundation for a future generation of neural science and medical devices. Although better sensory and motor prosthetics will be the early milestones in this endeavor, a splendid consequence of research into learning to interact with associational regions of the brain will be a deeper understanding of how parts of the brain think their thoughts."--Steven J. Schiff, Krasnow Professor of Neurobiology, George Mason University "*Toward Replacement Parts for the Brain* is an excellent compilation of outstanding research and development efforts that covers much of the promise of this area and the progress being made in this emerging field. Key contributions in neural coding and sensory prosthetics are presented, as are subjects that must be addressed before these technologies can be realized, such as biocompatibility and events at the interface of living and non-living systems. History will look back at this field and recognize this book as a key contribution to recognizing the tremendous goals and of the people pursuing them."--Alan S. Rudolph, former Chief of Biological Science and Technology at the Defense Advanced Research Projects Agency (DARPA)

Prefacep. vii
Sensory Systems
We Made the Deaf Hear. Now What?p. 3
Microelectronic Array for Stimulation of Large Retinal Tissue Areasp. 15
Imaging Two-Dimensional Neural Activity Patterns in the Cat Visual Cortex using a Multielectrode Arrayp. 43
Neural Representations
Brain Parts on Multiple Scales: Examples from the Auditory Systemp. 69
A Protocol for Reading the Mindp. 91
Cognitive Processes in Replacement Brain Parts: A Code for All Reasonsp. 111
Mathematical Modeling as a Basic Tool for Neuromimetic Circuitsp. 129
Real-Time Spatiotemporal Databases to Support Human Motor Skillsp. 159
Neuron/Silicon Interfaces
Long-Term Functional Contact between Nerve Cell Networks and Microelectrode Arraysp. 177
Building Minimalistic Hybrid Neuroelectric Devicesp. 205
The Biotic/Abiotic Interface: Achievements and Foreseeable Challengesp. 221
Hardware Implementations
Brain-Implantable Biomimetic Electronics as a Neural Prosthesis for Hippocampal Memory Functionp. 241
Brain Circuit Implementation: High-Precision Computation from Low-Precision Componentsp. 277
Hybrid Electronic/Photonic Multichip Modules for Vision and Neural Prosthetic Applicationsp. 295
Reconfigurable Processors for Neural Prosthesesp. 335
The Coming Revolution: The Merging of Computational Neural Science and Semiconductor Engineeringp. 369
Contributorsp. 385
Indexp. 389
Table of Contents provided by Ingram. All Rights Reserved.

ISBN: 9780262025775
ISBN-10: 0262025779
Series: A Bradford Book
Audience: Professional
For Ages: 18+ years old
Format: Hardcover
Language: English
Number Of Pages: 480
Published: 1st June 2005
Publisher: MIT Press Ltd
Country of Publication: US
Dimensions (cm): 22.9 x 17.8  x 3.2
Weight (kg): 0.98