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Therapy for Viral Hepatitis and Prevention of Hepatocellular Carcinoma - M. Omata

Therapy for Viral Hepatitis and Prevention of Hepatocellular Carcinoma

By: M. Omata (Editor), K. Okita (Editor)

Hardcover

Published: January 2004
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The first single-topic annual conference on hepatology in Japan was held in November 2002 to discuss therapies for viral hepatitis and the prevention of hepatocellular carcinoma (HCC). Bringing together researchers and clinicians from North America, Europe, Japan, and other parts of Asia, the conference included symposia on the hepatitis C replicon system, new antivirals that lower or prevent the incidence of HCC, and transplantation in cases of hepatitis B and C, as well as new treatment modalities for viral hepatitis and preventative measures for HCC. With the rising number of HCC cases worldwide, this collection of papers presented at the conference provides a valuable, up-to-date resource and reference for all professionals involved in the treatment and prevention of viral hepatitis and hepatocellular carcinoma.

Inaugurating the Single-Topic Conferencep. V
Prefacep. VII
Organization of the Symposiump. XI
Therapy for Viral Hepatitis and Prevention of Hepatocellular Carcinoma
Opening Lecture: What is Accomplished and What is Neededp. 3
Lamivudine Therapy for Hepatitis B
New Anti-Virals Against Wild-Type and Lamivudine-Resistant Hepatitis B Virusp. 25
Lamivudine Therapy of Hepatitis B in Japanp. 32
Early Detection of Lamivudine Resistant Mutant in Chronic Hepatitis B Patients Using a Novel Sensitive Methodp. 38
New Anti-Virals: HBV
New Antiviral Treatment for Chronic Hepatitis Bp. 47
New Antiviral Therapy: Adefovir Dipivoxil for HBVp. 57
Development of Entecavir: Superior Therapy for the Management of Chronic Hepatitis B Viral Infectionp. 63
Therapy for Hepatitis B and Prevention of HCC
Therapy of Hepatitis B and Prevention of Hepatocellular Carcinomap. 77
Differences of Clinical Characteristics Among Japanese Patients with Hepatitis B Virus Genotypes B and Cp. 84
HCV Replicon System
Establishment of a New Hepatitis C Virus-1b Repliconp. 97
Hepatitis C Virus Replication in Cell Culturep. 108
Characterization of the Interferon Alpha Response Against HCV in Hepatoma Cellsp. 123
New Anti-Virals: HCV
Hepatitis C: Development of a Ribavirin Liver-Targeting Prodrugp. 133
HCV Replicon Inhibitors: Mode of Action and Resistance Mappingp. 140
Interferon Therapy for Hepatitis C
Interferon Treatment Not Only Reduces the Risk of Hepatocellular Carcinoma But Also Improves Mortality in Patients with Chronic Hepatitis C Showing Biochemical Response, Especially in Patients with Advanced Liver Fibrosisp. 157
Favorable Outcome of Patients with C-Viral Liver Disease Treated with Interferonp. 167
IFN Receptor and IFN Signalsp. 176
Therapy for Hepatitis C and Prevention of HCC
Management and Treatment of Hepatitis Cp. 189
Hepatitis C Virus and Hepatocellular Carcinomap. 199
Randomized Trial of Post-Operative Interferon Therapy After Resection of Hepatitis C Virus-Related Hepatocellular Carcinoma and Long-Term Outcomep. 209
Roles of Antiviral Therapy in Chronic Hepatitis C Patients Should be Different According to the Stages of Liver Disease Progressionp. 219
Significance of Sustained Inflammation in the Development of HCC from HCV-Associated Cirrhotic Patients and the Prevention of HCC by Anti-Inflammatory Agentsp. 229
Chemoprevention and Therapy for HCC
Chemoprevention of Hepatocellular Carcinoma with Retinoidp. 241
Vitamin K[subscript 2] Administration Improves the Prognoses of Patients with Hepatocellular Carcinoma Presenting High Levels of Serum Des-[gamma]-Carboxy Prothrombinp. 249
Combination Chemotherapy for Advanced Hepatocellular Carcinomap. 251
Combined Intra-Arterial 5-Fluorouracil and Subcutaneous Interferon-Alpha Therapy for Advanced Hepatocellular Carcinoma with Tumor Thrombi in the Major Portal Branchesp. 258
Transplantation for HBV and HCV
Liver Transplantation for Hepatitis B Virus-Related Liver Diseasep. 273
Living Donor Liver Transplantation for Hepatitis B and C Cirrhosisp. 283
Living Donor Liver Transplantation for HBV-/HCV-Related Diseasesp. 293
Table of Contents provided by Rittenhouse. All Rights Reserved.

ISBN: 9784431402800
ISBN-10: 4431402802
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 295
Published: January 2004
Publisher: Springer Verlag, Japan
Country of Publication: JP
Dimensions (cm): 23.5 x 15.5  x 1.91
Weight (kg): 6.64