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The Sepsis Text - Prof. Jean-Louis Vincent

The Sepsis Text

By: Prof. Jean-Louis Vincent (Editor), Jean Carlet (Editor), Steven M. Opal (Editor)

Hardcover

Published: 28th February 2002
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This textbook is written at the dawn of a new era in the management of sepsis. Recent achievements in the clinical management of septic shock are the culmination of decades of basic and applied research by innovative researchers and clinical investigators worldwide. The contributing authors to this book have spearheaded much of this research and the Editors have endeavored to create a textbook that is comprehensive in nature while maintaining a specific focus upon the multitude of work that constitutes the spectrum of sepsis research including: pathophysiology; monitoring systems; general support; microbial aspects; complications; and anti-sepsis therapies.

"The goald of the editors of The Sepsis Text was to provide a comprehensive review of recent achievements in the management of sepsis, based on basic and applied research performed in recent years by innovative scientists and clinical investigators worldwide ... excellent chapter on coagulation ...The editors and contributing authors should be congratulated for their excellent reviews of recent progress in our understanding of sepsis and in its management. The Sepsis Text clearly conveys their enthusiasm and provides encouragement to all those working in the field."
(Greet Van den Berghe, Catholic University of Leuven in The New England Journal of Medicine, 347:15 (2002)

Contributors
Introduction
Sepsis: The magnitude of the problemp. 1
Diagnosis and source of sepsis: The utility of clinical findingsp. 11
Organ failurep. 29
Markers of sepsisp. 47
Genetic predispositionp. 67
Quantifying risk in sepsis: A review of illness severity and organ dysfunction scoringp. 81
The pathogenesis of Gram-negative sepsisp. 97
The pathophysiology of Gram-positive shockp. 117
Immunopathogenesis of Gram-negative shockp. 135
Involvement of pro- and anti-inflammatory cytokines in sepsisp. 159
Pathophysiology of immunodepression in ICU patientsp. 197
Pathophysiology of sepsis: the role of nitric oxidep. 211
Apoptosis and the resolution of inflammation in sepsisp. 231
Microvascular alterations in sepsisp. 247
Cytopathic hypoxiap. 271
Invasive hemodynamic monitoringp. 285
Value of SvO[subscript 2] in sepsisp. 309
Blood lactate concentrations in sepsisp. 323
Veno-arterial PCO[subscript 2] gradientp. 339
Gas tonometryp. 353
General hemodynamic supportp. 375
Fluid administrationp. 389
Blood transfusion and sepsisp. 401
Catecholamine therapyp. 421
Regional effects of catecholaminesp. 445
Management of respiratory dysfunction in patients with severe sepsisp. 455
The role of nutritional support in sepsisp. 479
The sources of sepsisp. 491
Catheter-related sepsisp. 505
Control of the source of sepsisp. 525
Empirical antibiotic therapy for patients with severe sepsis and septic shockp. 539
Candida infections in the intensive care unitp. 559
Why, when and how to isolate ICU patientsp. 581
The lung in sepsisp. 609
The heart in sepsisp. 619
The brain in sepsisp. 633
The gut in sepsisp. 645
The kidney in sepsisp. 665
The coagulation system in sepsisp. 687
Should fever be treated in sepsis?p. 705
Anti-cytokine therapyp. 719
Heat shock proteins and sepsis: A hot storyp. 729
Immunodepression in the surgical patient and increased susceptibility to infectionp. 743
The place of corticosteroidsp. 757
The place of immunonutritionp. 769
Interference with the coagulation systemp. 787
Hemofiltration and plasmapheresisp. 801
Endotoxin analogs in the treatment of septic shockp. 815
Vaccines against bacterial endotoxinsp. 827
Indexp. 837
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9780792376200
ISBN-10: 079237620X
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 848
Published: 28th February 2002
Publisher: Springer
Country of Publication: NL
Dimensions (cm): 23.5 x 15.5  x 4.06
Weight (kg): 1.59