The Sepsis Text

By: Jean-Louis Vincent, Jean Carlet, Steven M. Opal

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Hardcover | 28 February 2002

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Hardcover
872 Pages

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23.5 x 16.51 x 3.81

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This textbook is written at the dawn of a new era in the management of sepsis. Recent achievements in the clinical management of septic shock are the culmination of decades of basic and applied research by innovative researchers and clinical investigators worldwide. The contributing authors to this book have spearheaded much of this research and the Editors have endeavored to create a textbook that is comprehensive in nature while maintaining a specific focus upon the multitude of work that constitutes the spectrum of sepsis research including: pathophysiology; monitoring systems; general support; microbial aspects; complications; and anti-sepsis therapies.

Industry Reviews

"The goald of the editors of The Sepsis Text was to provide a comprehensive review of recent achievements in the management of sepsis, based on basic and applied research performed in recent years by innovative scientists and clinical investigators worldwide ... excellent chapter on coagulation ...The editors and contributing authors should be congratulated for their excellent reviews of recent progress in our understanding of sepsis and in its management. The Sepsis Text clearly conveys their enthusiasm and provides encouragement to all those working in the field."
(Greet Van den Berghe, Catholic University of Leuven in The New England Journal of Medicine, 347:15 (2002)

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Contributors
Introduction
Sepsis: The magnitude of the problem	p. 1
Diagnosis and source of sepsis: The utility of clinical findings	p. 11
Organ failure	p. 29
Markers of sepsis	p. 47
Genetic predisposition	p. 67
Quantifying risk in sepsis: A review of illness severity and organ dysfunction scoring	p. 81
The pathogenesis of Gram-negative sepsis	p. 97
The pathophysiology of Gram-positive shock	p. 117
Immunopathogenesis of Gram-negative shock	p. 135
Involvement of pro- and anti-inflammatory cytokines in sepsis	p. 159
Pathophysiology of immunodepression in ICU patients	p. 197
Pathophysiology of sepsis: the role of nitric oxide	p. 211
Apoptosis and the resolution of inflammation in sepsis	p. 231
Microvascular alterations in sepsis	p. 247
Cytopathic hypoxia	p. 271
Invasive hemodynamic monitoring	p. 285
Value of SvO[subscript 2] in sepsis	p. 309
Blood lactate concentrations in sepsis	p. 323
Veno-arterial PCO[subscript 2] gradient	p. 339
Gas tonometry	p. 353
General hemodynamic support	p. 375
Fluid administration	p. 389
Blood transfusion and sepsis	p. 401
Catecholamine therapy	p. 421
Regional effects of catecholamines	p. 445
Management of respiratory dysfunction in patients with severe sepsis	p. 455
The role of nutritional support in sepsis	p. 479
The sources of sepsis	p. 491
Catheter-related sepsis	p. 505
Control of the source of sepsis	p. 525
Empirical antibiotic therapy for patients with severe sepsis and septic shock	p. 539
Candida infections in the intensive care unit	p. 559
Why, when and how to isolate ICU patients	p. 581
The lung in sepsis	p. 609
The heart in sepsis	p. 619
The brain in sepsis	p. 633
The gut in sepsis	p. 645
The kidney in sepsis	p. 665
The coagulation system in sepsis	p. 687
Should fever be treated in sepsis?	p. 705
Anti-cytokine therapy	p. 719
Heat shock proteins and sepsis: A hot story	p. 729
Immunodepression in the surgical patient and increased susceptibility to infection	p. 743
The place of corticosteroids	p. 757
The place of immunonutrition	p. 769
Interference with the coagulation system	p. 787
Hemofiltration and plasmapheresis	p. 801
Endotoxin analogs in the treatment of septic shock	p. 815
Vaccines against bacterial endotoxins	p. 827
Index	p. 837
Table of Contents provided by Blackwell. All Rights Reserved.

The Sepsis Text

At a Glance

Hardcover

Industry Reviews

Shipping

How to return your order

Defective items

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