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The Role of Nitric Oxide in Heart Failure - Bodh I. Jugdutt

The Role of Nitric Oxide in Heart Failure

By: Bodh I. Jugdutt (Editor)

Hardcover

Published: 30th April 2004
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Research in the field of nitric oxide (NO) has grown exponentially since 1998, when three prominent researchers were recognized by Nobel prize awards. With the expansion in knowledge and the growing number of publications on the role of NO in several disciplines, it has become necessary to separately review the current knowledge of the role of NO in the pathophysiology and therapeutics of the major cardiovascular diseases, such as coronary artery disease and atherosclerosis, acute coronary syndromes and myocardial infarction, and heart failure. The emerging literature on the therapeutic implications of NO in pulmonary hypertension is also reviewed. This first volume is a compilation of a series of comprehensive review articles on selected topics that were published in the Journal of Heart Failure Reviews. The 20 excellent articles were contributed by some of the leading basic and clinician scientists in the field. The articles are well balanced and address clinically pertinent issues. The book should serve as an excellent reference source for basic science and medical students, medical residents and postdoctoral fellows, pharmacologists, physicians, cardiologists, cardiovascular su

Foreword
Preface
Acknowledgements
No and Pathophysiology of Heart Failure
Nitric Oxide in Heart Failure: Friend or Foe
No and the Vasculature: Where Does It Come from and What Does It Do?
Myocardial Contractile Effects of Nitric Oxide Walter
Nitric Oxide, Platelet Function, Myocardial Infarction and Reperfusion Therapies
Nitric Oxide, Atherosclerosis and the Clinical Relevance of Endothelial Dysfunction
Regulation of Cardiac Remodeling by Nitric Oxide: Focus on Cardiac Myocyte Hypertrophy and Apoptosis
Role of Nitric Oxide in the Pathophysiology of Heart Failure
Nitric Oxide, Cell Death, and Heart Failure
Acute and Chronic Endothelial Dysfunction: Implications for the Development of Heart Failure
The Role of NOS in Heart Failure: Lessons from Murine Genetic Models
No and Cardiovascular Therapeutics
Nitric Oxide and Cardiovascular Protection
Angiotensin II and Nitric Oxide Interaction
The Nitric Oxide-Endothelin-1 Connection
The Therapeutic Effect of Natriuretic Peptides in Heart Failure; Differential Regulation of Endothelial and Inducible Nitric Oxide Synthases
Mechanisms Underlying Nitrate-Induced Endothelial Dysfunction: Insight from Experimental and Clinical Studies
Statins and the Role of Nitric Oxide in Chronic Heart Failure
Role of Nitric Oxide in Matrix Remodeling in Diabetes and Heart Failure
Peroxynitrite in Myocardial Ischemia-Reperfusion Injury
The Role of the NO Axis and its Therapeutic Implications in Pulmonary Arterial Hypertension
Nitric Oxide and Cardioprotection During Ischemia-Reperfusion
Index
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9781402077364
ISBN-10: 140207736X
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 252
Published: 30th April 2004
Publisher: Springer-Verlag New York Inc.
Country of Publication: US
Dimensions (cm): 27.9 x 21.0  x 1.91
Weight (kg): 1.22