The Role of Interleukin-2 in the Treatment of Cancer Patients

By: J. Wagstaff (Editor)

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Hardcover
204 Pages

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23.0 x 16.51 x 1.91

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Recombinant human interleukin-2 became available for clinical use in the mid 1980s. Recent years have seen an enormous amount of clinical research with this cytokine and interleukin-2 has now been registered for use in a number of European countries for the treatment of metastatic renal cell carcinoma. This book is designed to provide the clinical oncologist wishing to use interleukin-2 with a basic background concerning the biology of the agent, a discussion concerning practical aspects, of its clinical use including management of toxicity and an overview of the clinical results together with a description of how this internesting cytokine might be developed in the future.

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Non-Fiction Medicine Clinical & Internal Medicine Diseases & Disorders Immunology Oncology Infectious & Contagious Diseases

Preface
List of Contributors
Introduction	p. 1
Interleukin-2 as a single agent: dose, scheduling and optimum immunomodulatory dose	p. 7
Interleukin-2 and lymphokine activated killer (LAK) cells	p. 29
Interleukin-2 toxicity: mechanisms and management	p. 45
Interleukin-2: biology and immunology	p. 71
Interleukin-2 and tumour eradication by cytotoxic T lymphocytes	p. 85
Combination treatment with Interleukin-2 and chemotherapeutic agents	p. 95
Interleukin-2, lymphocytes and monoclonal antibodies	p. 123
Interleukin-2 and other cytokines	p. 141
Future prospects for Interleukin-2 therapy	p. 169
Index	p. 187
Table of Contents provided by Blackwell. All Rights Reserved.

The Role of Interleukin-2 in the Treatment of Cancer Patients

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Hardcover

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