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The Progress of Experiment : Science and Therapeutic Reform in the United States, 1900-1990 - Harry M. Marks

The Progress of Experiment

Science and Therapeutic Reform in the United States, 1900-1990

Hardcover

Published: 2nd July 2010
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This book explores the origins of our contemporary system of drug regulation and the modern clinical trial. Marks illustrates the symbiotic relationship between the history of modern drug regulation and the history of therapeutic reform. Accompanying this history of public policy is a detailed account of changing experimental ideals and practices. Marks traces the history of therapeutic experimentation, from the "collective investigations" of the past century to the controlled clinical trial that emerged after 1950 as the paradigm of scientific experimentation. The result is the first general history of clinical research in the United States, a book that examines therapeutic experiments in a wide range of diseases, from syphilis and pneumonia to heart disease and diabetes.

'Harry Marks' book on science and therapeutic reform in the USA during the 20th century is the best available account of the progress of clinical experiment available, and nobody seriously interested in the topic can afford not to read it.' Endeavour ' ... the book has become essential reading for anyone thinking about the place of science within twentieth-century medicine.' Medical History 'The Progress of Experiment is a book rich in empirical detail, all meticulously documented in long footnotes. ... this book makes for interesting reading for anybody interested in arriving at a historically based judgement on the potential scope and limits of evidence-based medicine. With its detailed, well-researched case studies it will also provide good course reading. It is laudable that the paperback edition makes this book available to a wider group of potential readers.' The British Society for the History of Science

Acknowledgmentsp. ix
List of abbreviationsp. xii
Introductionp. 1
Of Institutions and Character: the Era of Organizational Reformp. 15
A rational therapeuticsp. 17
Memories of underdevelopment: Therapeutic research in the United States, 1900-1935p. 42
Playing it safe: The Federal Food, Drug and Cosmetic Act of 1938p. 71
War and peacep. 98
Of Methods and Institutions, or the Triumph of Statisticsp. 129
Managing chance: Statistics and therapeutic experiments, 1950-1960p. 136
You gotta have heartp. 164
Anatomy of a controversy: The University Group Diabetes Program studyp. 197
The dreams of reason: Retrospect and prospectp. 229
A note on sourcesp. 249
Indexp. 253
Table of Contents provided by Syndetics. All Rights Reserved.

ISBN: 9780521581424
ISBN-10: 0521581427
Series: Cambridge History of Medicine
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 272
Published: 2nd July 2010
Publisher: CAMBRIDGE UNIV PR
Country of Publication: GB
Dimensions (cm): 22.86 x 15.24  x 1.91
Weight (kg): 0.57