Henrietta, privileged and sheltered, expected a smoothly comfortable society life in Washington when she married Sam Pollitt, a handsome self-made biologist. Ten years later, Henny is a skinny, screaming drudge with five children, a raging wreck of a woman driven by 'hate, horror, passion or contempt'. But Sam, whose impractical idealism has brought his family to near-ruin, is unchanged: still at sea in all adult affairs, an absurd hypocritical buffoon but a genius with children, except Louie, his eldest daughter, an ugly, brilliant adolescent who is forced to take a drastic final step to save herself and the children from lasting tragedy.