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The Lactoperoxidase System : Chemistry and Biological Significance - Kenneth Pruitt

The Lactoperoxidase System

Chemistry and Biological Significance

Hardcover

Published: 1st March 1985
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This important, new reference is the first single source devoted to the lactoperoxidase system, examining the full range of biochemical and biological aspects of this nonimmunoglobulin defense factor and reviewing the current status of potential clinical applications. Emphasizing the role of the various nonantibody defense systems in protection from viruses, bacteria, and other microorganisms, The Lactoperoxidase System covers the antimicrobial mechanisms of lactoperoxidase, offering varied perspectives regarding attempts to enhance the antimicrobial properties of peroxidase systems for therapeutic uses ... details the basic biochemistry of peroxidase-catalyzed oxidation and halogenation reactions, promoting understanding of the vital function of oxidative enzymes in protecting mucosal surfaces ... treats the problems of collection, treatment, and analysis of mammaliam exocrine secretions, helping improve laboratory techniques and data interpretation ... and includes more than 800 references, facilitating access to the widely scattered literature. Providing the insight and experience of 13 leading international researchers, The Lactoperoxidase System will be an invaluable reference for microbiologists, immunologists, and biochemists; dentists, oral pathologists, and oral biologists; veterinarians and dairy scientists; and medical and dental students. Moreover, the book is an ideal text on the subject for graduate-level courses in microbiology, immunology, and clinical dentistry. Book jacket.

Prefacep. iii
Contributorsp. vii
The Biological Significance of the Nonimmunoglobulin Defense Factorsp. 1
The Chemical Structure of Lactoperoxidasep. 15
Products of Lactoperoxidase-Catalyzed Oxidation of Thiocyanate and Halidesp. 31
Steady-State Kinetics of Lactoperoxidase-Catalyzed Reactionsp. 55
Genetic Variation of Salivary Peroxidasep. 89
The Peroxidase System in Human Secretionsp. 101
The Lactoperoxidase System of Bovine Milkp. 123
Biochemistry of Peroxidase System: Antimicrobial Effectsp. 143
Bacterial Hydrogen Peroxide Productionp. 179
Effect of Sugars and Sugar Alcohols on Salivary Peroxidasep. 203
Activation of the Salivary Peroxidase Antimicrobial System: Clinical Studiesp. 217
Antibody Targeting of the Antimicrobial and Antitumor Activity of the Peroxidasesp. 229
Indexp. 243
Table of Contents provided by Ingram. All Rights Reserved.

ISBN: 9780824772987
ISBN-10: 0824772989
Series: Immunology Series
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 257
Published: 1st March 1985
Publisher: TAYLOR & FRANCIS
Country of Publication: US
Dimensions (cm): 23.57 x 15.14  x 2.08
Weight (kg): 0.59
Edition Number: 1