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The Genetics of Alcoholism : Alcohol and Alcoholism - Henri Begleiter

The Genetics of Alcoholism

Alcohol and Alcoholism

By: Henri Begleiter (Editor), Benjamin Kissin (Editor)

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This volume provides an in-depth look at the genetic influences that contribute to the development of alcoholism. Part I: Epidemiologic Studies contains five chapters that examine the various approaches employed in the study of the genetics of alcoholism. It provides a historical perspective and details all the essentials of this subject. Part II: Selective Breeding Studies highlights the results of research involving the selective breeding of rodents. This type of research has produced homogenous strains exhibiting specific behavioral responses considered significant in the development and maintenance of alcohol dependence. The studies presented in Part III: Phenotypic Studies investigate and analyze phenotypic markers that serve as correlates to the genotypic determinants of alcoholism. Through its broad scope, this volume provides for the first time a panoramic view of the knowledge available on the hereditary influences of alcoholism.

"An extraordinarily concise and comprehensive look at the studies conducted by scientists in their efforts to define and treat this prevalent and destructive illness...Thorough, well-organized and directed in its approach. Presenting complex material for a diverse audience is never easy, but given the scope of this work, coupled with the fact that there were multiple contributing authors, this is an excellent text."--Applied Cytogenetics "A timely and well-integrated review of the genetics of alcoholism...A strong point for this book is its depth and scholarly referencing of evidence for major points....I recommend this book to a broad range of clinicians as well as researchers who are interested in up-to-date and comprehensive review of the genetics of alcoholism...as well as concise reviews of powerful methods of genetic methodology...An excellent opportunity to broaden one's understanding of the genetics of this most important and destructive disorder."--The Journal of Nervous and Mental Disease

PART I: Genetic Epidemiology 1: V.M. Hesselbrook: The Genetic Epidemiology of Alcoholism 2: M.N. Hesselbrook: Genetic Determinants of Alcoholic Subtypes 3: R.J. Cadoret: Familial Transmission of Psychiatric Disorders Associated with Alcoholism 4: A.C. Heath: Genetic Influences on Drinking Behavior in Humans 5: J.R. Wilson and E. Laffan: Alcohol Metabolism, Sensitivity and Tolerance: Testing for Genetic Influences PART II: Laboratory Studies in Animals and Humans of Genetic Influences in Alcoholism 6: R.A. Deitrich and R.C. Baker: Genetic Influences on Alcohol Metabolism and Sensitivity to Alcohol in Animals 7: L. Lumeng et al.: Genetic Influences on Alcohol Preference in Rodents 8: D.W. Crabb et al.: Genetic Factors that Reduce Risk for Developing Alcoholism 9: A.E. Kosobud and J.C. Crabbe: Genetic Influences on the Development of Alcohol Physical Dependence and Withdrawal PART III: Strategies for Genetic Research in Alcoholism 10: I. Diamond and A. Gordon: Biochemical Markers for Genetic Alcoholism 11: H. Begleiter and B. Porjesz: Phenotypic Markers for the Development of Alcoholism 12: R. Tarter, H.E. Moss and M.M. Vanyukov: Behavior Genetics and the Etiology of Alcoholism 13: G.E. McClearn and R. Plonim: Strategies for the Search for Genetic Influences in Alcohol-Related Phenotypes 14: A.F. Wilson and R.C. Elston: Linkage Analysis in the Study of the Genetics of Alcoholsim

ISBN: 9780195088779
ISBN-10: 0195088778
Series: Alcohol and Alcoholism
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 410
Published: 18th May 1995
Country of Publication: US
Dimensions (cm): 24.1 x 17.1  x 2.8
Weight (kg): 0.83