Many advances have been made in the field of thermoregulation in the past few years. These include our understanding of Fever, which is now considered not simply a rise in deep body temperature foHowing infection, but just one aspect, though perhaps the most easily measured, of the Acute Phase of the Immune Response. Classification and identification of the Cytokines and the availability of recombinant material has greatly aided this research. Similarly, our understanding of the Hypothalamo-Pituitary Adrenal Axis has altered our way of thinking about temperature regulation. Of importance are the problems associated with adverse climatic conditions and survival, and the problems encountered by the neonate and the hibernator. At the biochemical level, our knowledge of the control of heat production and the role of brown adipose tissue is rapidly advancing. All these issues and many others were discussed at a Symposium 'Thermal Physiology 1993' held in Aberdeen, Scotland in August 1993 under the auspices of the Thermal Physiology Commission of the International Union of Physiological Sciences. Six main aspects of the subject of temperature regulation are included in this book, namely, Fever (including the Acute Phase of the Immune Response and Thermoregulatory Peptides), Neurophysiology of Thermoregulation, Neonatal Thermoregulation, Mechanisms of Heat Production, Ecological and Behavioural Thermoregulation, and Emerging Themes in Thermoregulation.
Effect of peripheral corticotrophin-releasing factors on febrile responses, N.G.N. Milton; fever induction by a cytokine network in guinea pigs - the roles of tumor necrosis factor and interleukin-6, J. Roth et al; cytokines in endotoxin tolerance, E. Zeisberger et al; effects of immunomodulators and protease inhibitors on fever, P.P. Murzenok and V.N. Gourine; endogenous steroids limit the magnitude of febrile responses, J. Davidson; the role of heat shock proteins (HSPs) and interleukin-1 interaction in suppression of fever, M. Kosaka et al; body temperature elevation per se induces the late phase syndrome, A.A. Romanovsky and C.M. Blatteis; the absence of fever in rat malaria is associated with increased turnover of 5-hydroxytryptamine in the brain, M.J. Dascombe and J.Y. Sidara; prostaglandins and the acute phase immune response, D. Rotonda; pyrogenic immunomodulator stimulation of a novel thymic corticotrophin releasing factor in vitro, N.G.N. Milton et al; apparent dissociation between lipopolysaccharide-induced intrapreoptic release of prostaglandin E and fever in guinea pigs, M. Szekely et al; thermoregulatory responses of rabbits to combined heat exposure, pyrogen and dehydration, C.M. Blatteis et al; fever and the organum vasculosum laminae terminals - another look, W.S. Hunter et al; lipopolysaccharide (LPS)-induced FOS expression in the brains of febrile rats, A. Oladehin et al; analysis of body temperature and blood protein in hypothermic syrian hamsters and rats, N. Ohwatari et al; neurophysiology of thermoregulation - role of hypothalamic neuronal networks, J.A. Boulant; effect of 5-HT receptor agonists or antagonists on hypothalamic 5-HT release or colonic temperature in rats, M.T. Lin and H.J. Liu; temperature sensitivity of rat spinal cord neurons recorded in vitro, H.A. Schmid et al; the effect of ambient temperature on the modulation of thermoregulatory mechanisms by selective opioid peptides, C.M. Handler et al; regulation of body temperature - involvement of opioid and hypothalamic gaba, S. Ghosh (nee Biswas) and M.K. Poddar; bilateral difference in tympanic temperatures reflects that in brain temperature, T. Ogawa et al; temperature interhemispheric brain asymmetry as a sign of functional activity, I.K. Yaitchnikov and V.S. Gurevitch; cerebral and related temperatures in normothermic subjects, Z. Mariak et al; non-thermometric means of assessing changes of brainstem temperature - the question of selective brain cooling in humans, T. Langer et al; effects of selective alpha-adrenergic blockade on control of human skin blood flow during exercise, W.L. Kenney; acclimation to 3 different climates with the same wet bulb globe temperature, B. Griefahn and P. Schwarzenau; sensible heat loss after systemic anti cholinergic treatment, M.A. Kolka et al; neuropeptide-Y (NPY) reduces cutaneous microcirculatory blood flow and increases total blood flow in the rat tail, M.E. Heath. (Part contents).
Series: Advances in Pharmacological Sciences
Number Of Pages: 376
Published: 1st February 1994
Publisher: SPRINGER VERLAG GMBH
Country of Publication: CH
Dimensions (cm): 23.39 x 15.6
Weight (kg): 0.72