"A continuous flow of ideas, activities, and applications. The author, who has worked with supramolecular synthons for close on three decades, tells the story admirably. This book, full of facts and figures, will be important for researchers in both academic and corporate worlds, for both novitiates and experts."
Gautam R. Desiraju, Indian Institute of Science, India
"Crystal Engineering is playing an increasingly important role in the development of active pharmaceutical ingredients. Being able to develop methods to prepare co-crystals and supramolecular complexes with desired properties is a key goal. This volume presents beginners in the field and researchers the information needed to work in this important area."
Allan S. Myerson, Massachusetts Institute of Technology, USA
"Ashwini Nangia's book on fundamentals and advanced research aspects of an extremely active area of pharmaceutical science, namely that of the design, preparation, characterization, and evaluation of the properties of crystalline forms of active ingredients. Anyone interested in crystal engineering applied to pharmaceutical compounds should read this book."
Dario Braga, Universita di Bologna and PolyCrystalLine, Italy
"The understanding and control of active ingredient solid form in pharmaceutical drug products has never been more important. This timely and useful book takes a holistic approach to crystal structure prediction and control and shows the importance of crystal engineering throughout the pharmaceutical product design and manufacturing process. The book ranges from the fundamental understanding of the organic solid state through modern strategies to screen and control crystal and particle properties and even includes very recent developments in the role generative AI can play in the pharmaceutical space. Nangia is one of the leaders in the development of solid form control strategies and this book is required reading for industry professionals, students, and researchers irrespective of their level of experience in pharmaceutical solids."
Jonathan W. Steed, Durham University, UK and Editor-in-Chief, Crystal Growth Design
"This book is an excellent primer to introduce students and professionals to the topic of cocrystals, with a nice historical overview, leading to design through supramolecular concepts, property optimization for performance, and scale up of cocrystal syntheses. I found the book to be a very readable compilation and the many excellent examples drive home the considerable progress that has been made in recent decades to translate supramolecular chemistry concepts to real world applications."
Susan M. Reutzel-Edens, Eli Lilly and SuRE Pharma Consulting, USA
"Prof. Nangia has produced an excellent text for both engaging the interest of and providing early direction to those interested in the emerging area of using crystal engineering to develop improved pharmaceuticals. There is enough meat to provide sound understanding of what has led to the current state-of-the-art and enough projection of how crystal engineering may revolutionize pharmaceuticals to pique interest and provide motivation to dig deeper. It is worth reading for those already working in the field, but I would heartily suggest the book to new investigators looking to make a big scientific impact."
Robin D. Rogers, University of Alabama, USA and Founding Editor-in-Chief, Crystal Growth Design