Preface.
Contributors.
PART 1 NEURONAL VOLTAGE-GATED ION CHANNEL FUNCTIONS.
1 Neuronal L-Type Voltage-Gated Calcium Channels (Alexander
Scriabine and David J. Triggle).
2 Voltage-Gated N-Type and T-Type Calcium Channels and
Excitability Disorders (Elizabeth Tringham and Terrance P.
Snutch).
3 Voltage-Gated Sodium Channels: Multiple Roles in the
Pathophysiology of Pain (Sulayman D. Dib-Hajj, Bryan C. Hains,
Joel A. Black, and Stephen G. Waxman).
4 The Role of Ion Channels in the Etiology and Development of
Gliomas (Amy K. Weaver and Harald Sontheimer).
5 Shaker Family Kv1 Voltage-Gated Potassium Channels in
Mammalian Brain Neurons (Helene Vacher and James S.
Trimmer).
6 Unique Mitochondrial Ion Channels: Roles in Synaptic
Transmission and Programmed Cell Death (Elizabeth A.
Jonas).
7 Regulation of Neuronal Excitability by the Sodium-Activated
Potassium Channels Slick (SLO2.1) and Slack (SLO2.2) (Valentin
K. Gribkoff and Leonard K. Kaczmarek).
PART 2 MODULATORY MECHANISMS AND INFLUENCES ON NEURONAL
VOLTAGE-GATED ION CHANNEL FUNCTION.
8 Alternative Splicing of Neuronal Cav2 Calcium Channels
(Diane Lipscombe, Summer E. Allen, Annette C. Gray, Spiro
Marangoudakis, and Jesica Raingo).
9 Effect of Hypoxia/Ischemia on Voltage-Dependent Channels
(Xiang Q. Gu, Hang Yao, and Gabriel G. Haddad).
10 In Vivo Roles of Ion Channel Regulatory Protein Complexes in
Neuronal Physiology and Behavior (Smitha Reddy, Mohammad
Shahidullah, and Irwin B. Levitan).
11 Regulation of Neuronal Ion Channels by G-Protein-Coupled
Receptors in Sympathetic Neurons (Mark S. Shapiro and Nikita
Gamper).
12 BK Channels: Regulation of Expression and Physiological
Impact (P. Kundu, A. Alioua, Y. Kumar, R. Lu, J. Ou, E.
Sanchez-Pastor, M. Li, E. Stefani, and L. Toro).
13 Structural Basis for Auxiliary KChIP Modulation of Kv4
Channels (KeWei Wang and Jijie Chai).
PART 3 DRUG DISCOVERY TARGETS AND TECHNOLOGY.
14 Sodium Channel Blockers for the Treatment of Chronic Pain
(Mark R. Bowlby and Edward Kaftan).
15 Neuronal Kv7 Potassium Channels as Emerging Targets for the
Treatment of Pain (Steven I. Dworetzky and Valentin K.
Gribkoff).
16 Small-Molecule Modulators of Large-Conductance,
Calcium-Activated (BK) Channels (John E. Starrett Jr.).
17 High-Throughput Screening Technologies in Ion Channel Drug
Discovery (Edward B. Stevens, Andrew D. Whyment, and J. Mark
Treherne).
Index.