Stimuli-Responsive Biomaterials for Inflammatory Diseases

Advances in Research and Clinical Applications

By: Vetriselvan Subramaniyan

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eText | 29 April 2026 | Edition Number 1

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This book reviews the use of stimuli-responsive biomaterials in the diagnosis, treatment, and management of inflammatory diseases. It begins by providing a foundational understanding of inflammatory diseases and presents fundamental principles of stimuli-responsive biomaterials. This book provides insights into the characteristics of ideal biomaterials and the chemical principles that enable stimuli-responsive drug delivery systems to function effectively. A detailed classification of these advanced materials is presented based on their responsive triggers, such as pH, temperature, light, and biological signals. The application of stimuli-responsive biomaterials in cancer therapeutics is discussed, as is their use in addressing autoimmune disorders, including lupus and rheumatoid arthritis, through targeted treatment strategies. The book also covers the innovative uses of these materials in managing inflammatory arthritis and various bone disorders, focusing on targeted drug delivery and improved patient outcomes. Further, it examines the potential of these smart materials in treating neuroinflammatory and neurological disorders, cardiovascular and cerebrovascular diseases, and in managing diabetes and obesity. The book highlights the development and application of injectable hydrogels that respond to various stimuli and presents the role of artificial intelligence and machine learning in the design of smart drug delivery systems. This book is intended for researchers working in biomedical engineering, drug delivery, and pharmaceutical sciences.

Key Features:

Provides an in-depth review of stimuli-responsive biomaterials and their applications in the diagnosis, treatment, and management of inflammatory diseases
Presents classification of advanced biomaterials based on their responsive triggers, such as pH, temperature, light, and biological signals
Highlights the use of stimuli-responsive biomaterials in cancer theranostics, autoimmune disorders, and targeted treatment strategies
Emphasizes the development and application of injectable hydrogels and the integration of artificial intelligence in designing smart drug delivery systems
Examines in-depth explanations of the chemical principles and mechanisms that enable stimuli-responsive drug delivery systems