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Stem Cells in Endocrinology : Contemporary Endocrinology - Linda B. Lester

Stem Cells in Endocrinology

Contemporary Endocrinology

By: Linda B. Lester (Editor)

Hardcover Published: 1st March 2005
ISBN: 9781588294074
Number Of Pages: 274

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A critical review by prominent experts of both the cutting-edge of stem cell biology and the application of stem cells to endocrine diseases, including diabetes, infertility, and liver-associated metabolic disorders. The authors discuss current research to modify stem cells, develop an endocrine-like cell, and use adult bone marrow stem cells to treat autoimmune diseases, including endocrine-based autoimmune diseases. Topics of interest include a review of all stem cell subtypes and their characteristics, approaches to promoting endocrine development from stem cells, and evidence for endocrine cell function from stem cells. The authors also outline how best to develop preclinical studies that will determine the safety and efficacy of stem cell therapies for endocrine disorders.

From the reviews:

"Stem Cells in Endocrinology considers the potential use of stem cells for the treatment of endocrine disorders. It consists of two sections, Basic Stem Cell Biology and Translational Research. ... The book as a whole is certainly of interest not only to specialists in the therapy of endocrine disorders, but also to those conducting stem cell research in general, and to motivated students." (Antonin Bukovsky, TRENDS in Endocrinology and Metabolism, Vol. 17 (6), August, 2006)

Embryonic stem cells : derivation, properties, and therapeutic implicationsp. 3
Germ line stem cellsp. 23
Umbilical cord stem cellsp. 49
Differentiation potential of adult stem cellsp. 67
Growth conditions for primate vs murine embryonic stem cellsp. 93
Islet precursor cells in adult pancreatic isletsp. 115
Transcription factor-directed differentiation of stem cells along an endocrine lineagep. 133
Generation of islet-like structures from ES cellsp. 147
The therapeutic potential of liver repopulation for metabolic or endocrine disordersp. 165
The manipulation of mesenchymal stem cells for bone repairp. 183
Spermatogenesis from transplanted spermatogenic stem cellsp. 207
Hematopoietic stem cell transplant in the treatment of autoimmune endocrine diseasep. 221
Preclinical trials for stem cell therapyp. 243
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9781588294074
ISBN-10: 1588294072
Series: Contemporary Endocrinology
Audience: General
Format: Hardcover
Language: English
Number Of Pages: 274
Published: 1st March 2005
Publisher: Humana Press Inc.
Country of Publication: US
Dimensions (cm): 23.5 x 15.5  x 2.46
Weight (kg): 1.29