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Statistics in Genetics : The IMA Volumes in Mathematics and its Applications - S. Geisser

Statistics in Genetics

The IMA Volumes in Mathematics and its Applications

By: S. Geisser (Editor), M.E. Halloran (Editor)

Hardcover Published: 4th June 1999
ISBN: 9780387988283
Number Of Pages: 238

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Though the Genome Project will eventually result in the sequencing of the human genome, as well as the genomes of several other organisms, there will still be a need for good statistics for family studies of complex diseases. The papers in this volume are contributions by some of the leading researchers in the field to the current topics in statistical genetics. One section deals with DNA sequence matching and issues related to forensics, while another deals with statistical problems of modeling phylogenies and inferential difficulties related to the complex tree structures produced, as well as the method of coalescence.

Foreword
Preface
The DNA typing controversy and NRC IIp. 1
In dispraise of inconsistent DNA relative frequency estimatesp. 25
Quantifying the genetic structure of populations with application to paternity calculationsp. 31
Coalescent theory and its applications in population geneticsp. 45
Phylogenies: An overviewp. 81
Detecting linked genomic mutationsp. 119
Biological and statistical studies for diseases involving mtDNA mutationsp. 133
Statistical methods in human geneticsp. 147
The affected-pedigree-member method revisited under population stratificationp. 165
Triangle constraints for sib-pair identity by descent probabilities under a general multilocus model for disease susceptibilityp. 181
A statistical analysis of cancer genome variationp. 223
List of participantsp. 237
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9780387988283
ISBN-10: 0387988289
Series: The IMA Volumes in Mathematics and its Applications
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 238
Published: 4th June 1999
Publisher: Springer-Verlag New York Inc.
Country of Publication: US
Dimensions (cm): 23.5 x 15.5  x 1.91
Weight (kg): 1.21