This study offers a broad conceptual and operational framework for a prompt global strike capability. It begins by establishing the historical context through the examination of preceding efforts to develop systems and technologies that could have supported prompt global strike operations. Next, it examines the capabilities of current and future systems including Conventional Ballistic Missiles, the Space Operations Vehicle, and hypersonic aircraft to conduct prompt global strike missions in order to develop a useful operational framework. Using this framework, the thesis then focuses on the broader implications of a rapid global strike capability. Specifically, it examines how well prompt global strike systems fit into existing Air Force doctrine and operational concepts. This study then examines some of the larger, strategic benefits of a prompt global strike system to include the potential coercive effects on adversaries. Finally, the thesis concludes with a summary of the major findings and conclusions and a series of recommendations on the next steps to take on the evolutionary path to a space and air force.