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Species and Specificity : An Interpretation of the History of Immunology - Pauline M.H. Mazumdar

Species and Specificity

An Interpretation of the History of Immunology

Hardcover Published: 29th September 1995
ISBN: 9780521431729
Number Of Pages: 476

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In the first hundred years of the history of immunology, the question of species and specificity were the core problems of research and practice in immunology. The old botanical dispute about the nature of species, which has its roots in the classical Western thought of Aristotle, reappeared in the late nineteenth century in the disputes of bacteriologists, to be followed by their students, the immunologists, immunochemists, and blood group geneticists. In the course of this controversy, Mazumdar argues, five generations of scientific protagonists make themselves aggressively plain. Their science is designed only in part to wrest an answer from nature: it is at least as important to wring an admission of defeat from their opponents. One of those on the losing side of the debate was the Austrian immunochemist Karl Landsteiner, whose unitarian views were excluded from the state health and medical institutions of Europe, where specificity and pluralism, the legacies of Robert Koch and Paul Ehrlich, were entrenched.

Industry Reviews

' ... you will have to read this fascinating book'. Richard A. Lake, The Times Higher Education Supplement 'Mazumdar has produced an immensely well-researched account.' Bernard Dixon, New Scientist 'It is perhaps the human cost of such encounters that makes Mazumdar's account of this particular conflict so enthralling.' British Journal for the History of Science 'Mazumdar's thesis is an important and persuasive one that deserves serious attention from anyone interested in 19th and 20th century biology.' John E. Lesch, Science 'This book is abundantly and well illustrated with many photographs.' Fred S. Rosen, Nature

Specificity and Unitarianism in XIX Century Botany and Bacteriology
The Unitarians
The Linnaeans
The dominance of specificity
The history of XIX century bacteriology from this point of view
The Inherited Controversy: Specificity and Unitarianism in Immunology
Dichotomy and classification in the thought Paul Erlich
Unity, simplicity, continuity: the philosophy
Chemical Affinity and Immune Specificity: The Argument in Chemical Terms
Structural and physical chemistry in the late XIX century
Erlich's chemistry and its opponents: the dissociation theory of Arrhenius Madsen
Erlich's chemistry and its opponents: the colloid theory of Landsteiner Pauli
Erlich's chemistry and its opponents: the new structural chemistry of Landsteiner Pick
The decline and persistence of Erlich's chemical theory
Absolute Specificity in Blood Group Genetics
Immunology and genetics in the early XX century
The specificity of cells and the specificity of proteins
The last confrontation
Conclusion
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780521431729
ISBN-10: 0521431727
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 476
Published: 29th September 1995
Publisher: CAMBRIDGE UNIV PR
Country of Publication: GB
Dimensions (cm): 22.86 x 15.24  x 3.02
Weight (kg): 0.87

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