The subject of smoking and the hormone disorders associated with it are of relatively recent interest. Its importance increases as the average age at death of the population increases and many of those people will have had a lifetime smoking. The book provides summaries of the present status of research into the effects of smoking and the apparent protection offered against certain diseases. Some research workers have suggested ways of predicting trends of disease patterns such as osteoporetic fractures. Not all the disorders discussed are adverse effects of smoking and these have provided impetus for developing non-tobacco methods of disease prevention. As the smoking population diminishes and the availability of lower tar brands increases, a reduction in many of the adverse disorders is expected and will form the basis for continued monitoring. This volume will appeal to a specialist audience of epidemiologists, pharmacologists, clinicians and those involved in public health policy.
'indispensable for anyone working on the epidemiology and aetiology of sex steroid-related disorders'
Journal of Smoking-Related Disorders
RESULTS FROM THREE PROSPECTIVE STUDIES: Smoking and oestrogen-related sites - data from American cancer studies; Smoking and hormone-related disorders in the Nurses' Health Study; Effects of cigarette smoking on `hormone-related' diseases in a Southern Californian retirement community; SMOKING, THE MENOPAUSE, AND THE BENIGN REPRODUCTIVE DISORDERS: Cigarette smoking and age at natural menopause; Hyperemesis gravidarum, uterine fibroids, and endometriosis:
effects of cigarette smoking on risk; Cigarette smoking and benign breast cancer; SMOKING AND OSTEOPOROSIS: Smoking and osteoporosis; Cigarette smoking and skin atrophy in women - a possible connection?;
Smoking and prostatic hypertrophy; Smoking and inflammatory bowel disease; Smoking and PArkinson's disease; SMOKING AND HORMONE-RELATED CANCERS: Cigarette smoking and the incidence of endometrial cancer; Cigarette smoking and cancer of the breast; Cigarette smoking and cancer of the large bowel; MECHANISMS: HORMONAL DIFFERENCES IN SMOKERS AND NON-SMOKERS: Smoking and endogenous sex hormones in men and women; Increased oxidative metabolism of oestrogens in male and female smokers; The effect of
smoking on hormone levels in vivo and steroid hormone biosynthesis in vitro. MECHANISMS: HORMONES OF POSSIBLE RELEVANCE TO SMOKING-RELATED DISEASES: Oestrogens and smoking-related disease: theoretical
considerations; Hormonal factors and cancers of the endometrium and breast; MECHANISMS: THE ROLE OF NICOTINE AND OTHER AGENTS IN TOBACCO SMOKE: Influence of nicotine and other components of tobacco smoke on oestradiol metabolism; Oestrogen 2-hydroxylation in rat and human liver; SUMMARY AND IMPLICATIONS: Smoking and hormone-related disorders: a summary of the evidence with implications for public health policy and future research.
Series: Oxford Medical Publications
Number Of Pages: 302
Published: 12th July 1990
Publisher: Oxford University Press
Country of Publication: GB
Dimensions (cm): 23.4 x 15.6
Weight (kg): 0.68