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Skeletal Muscle Repair and Regeneration : Advances in Muscle Research - Stefano Schiaffino

Skeletal Muscle Repair and Regeneration

Advances in Muscle Research

By: Stefano Schiaffino (Editor), Terence Partridge (Editor)

Hardcover Published: 30th January 2008
ISBN: 9781402067679
Number Of Pages: 379

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  • Paperback View Product Published: 22nd November 2010

Since the middle of the last century we have progressively built up a comprehensive descriptive model of the allied mechanisms that maintain our muscles at a size and strength appropriate to the functional demands upon them and that rapidly repair damaged muscles. This volume is an assemblage of the collective experience from the pick of major research groups investigating these aspects of muscle cell biology. The book adopts a non-specialist style of presentation from specialist researchers. The topics range from correlation of changes in pattern of gene expression with the histological sequence during a regenerative episode to the distinctive insult-specific patterns of structural and functional outcome at the other end of the spectrum. The middle ground - who is doing what in this complex process - constitutes the meat of this sandwich.

From the reviews:

"The book provides a broad discussion of skeletal muscle regeneration including historical aspects, animal models, stem cells, and reinnervation. The audience includes researchers and clinicians who work in the field of myopathy and neuropathy. ... The book is well written and comprehensive, the illustrations are adequate, and the references are up to date and complete. This multiauthored book on skeletal muscle regeneration is a good addition to the literature on this topic."(Mark Gonzalez, Doody's Review Service, November, 2008)

Prefacep. vii
Contributorsp. xi
Myogenesis - The Early Yearsp. 1
The Origin and Genetic Regulation of Myogenic Cells: From the Embryo to the Adultp. 19
The Muscle Satellite Cell: The Story of a Cell on the Edge!p. 45
Non Muscle Stem Cells and Muscle Regenerationp. 65
Transcriptional Cascades in Muscle Regenerationp. 85
The Ins and Outs of Satellite Cell Myogenesis: The Role of the Ruling Growth Factorsp. 107
Relaying the Signal During Myogenesis: Intracellular Mediators and Targetsp. 145
Muscle Regeneration in Animal Modelsp. 163
Skeletal Muscle Reconstitution During Limb and Tail Regeneration in Amphibians: Two Contrasting Mechanismsp. 181
Muscle Fibre Regeneration in Human Skeletal Muscle Diseasesp. 199
Skeletal Muscle Repair After Exercise-Induced Injuryp. 217
Inflammation in Skeletal Muscle Regenerationp. 243
Complexity of Extracellular Matrix and Skeletal Muscle Regenerationp. 269
Innervation of Regenerating Musclep. 303
Boosting Muscle Regenerationp. 335
Age-Dependent Changes in Skeletal Muscle Regenerationp. 359
Indexp. 375
Table of Contents provided by Ingram. All Rights Reserved.

ISBN: 9781402067679
ISBN-10: 1402067674
Series: Advances in Muscle Research
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 379
Published: 30th January 2008
Publisher: Springer-Verlag New York Inc.
Country of Publication: US
Dimensions (cm): 23.5 x 15.5  x 1.91
Weight (kg): 0.72