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Side-effects of Cancer Chemotherapy on the Gastrointestinal Tract : Pathophysiology, Prophylaxis and Therapy - M. Staritz

Side-effects of Cancer Chemotherapy on the Gastrointestinal Tract

Pathophysiology, Prophylaxis and Therapy

By: M. Staritz (Editor), E. Schmiegel (Editor), G. Adler (Editor), H.-J. Schmoll (Editor), A. Knuth (Editor)

Hardcover Published: 31st December 2003
ISBN: 9780792387916
Number Of Pages: 200

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Cancer chemotherapy frequently attacks the gastrointestinal tract. Many of the possible side-effects reduce the patient's quality of life, may limit acceptance of further drug administration, and even life-threatening complications must be considered. This book is the proceedings of the Falk Workshop 'Side-effects of Chemotherapy on the Gastrointestinal Tract: Pathogenesis and Therapy', held in Freiburg, Germany, on October 11, 2002 (Part IV of the Freiburg Gastroenterology Week). Chapters by pathologists, pharmacologists, oncologists and gastroenterologists will improve our understanding of the effects of anticancer agents on the organs of the gastrointestinal tract and help to compensate for chemotherapy-induced adverse effects.

List of Principal Contributors
Preface 1
Preface 2
Pharmacology of cancer chemotherapy drugsp. 3
Pharmacokinetically guided optimization and individualization of medical cancer chemotherapyp. 17
Pharmacokinetics of anticancer agents in patients with impaired liver functionp. 33
Pharmacodynamics of high-dose chemotherapyp. 55
Interactions of cytostatic drugsp. 73
Measurement approaches of quality of life in oncologyp. 79
Morphological changes of drug side-effects - view of the pathologistp. 91
Cell cycle of the mucosa and gland organs of the gastrointestinal system - physiology and influence of chemotherapeutic agentsp. 101
Side-effects of chemotherapy on the gastrointestinal tract: symptoms, grade and classificationp. 107
Central origin and psychosomatics of nausea and emesisp. 113
Cancer anorexia-cachexia syndrome - evidence in pathophysiology and managementp. 120
Mucositisp. 128
Neutropenic enterocolitis, enteric infectionsp. 142
Management of chemotherapy-induced diarrhoeap. 148
Disturbances of pancreatic exocrine function, pancreatitisp. 166
Chemotherapy and liver functionp. 170
Specific immunotherapy, angiogenesis inhibitors, gene therapy and other approaches: do we still need chemotherapy?p. 181
Indexp. 185
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9780792387916
ISBN-10: 0792387910
Series: Falk Symposium : Book 132
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 200
Published: 31st December 2003
Publisher: Springer
Country of Publication: NL
Dimensions (cm): 23.5 x 15.5  x 1.91
Weight (kg): 1.05