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RNA Biochemistry and Biotechnology : NATO Science Partnership Sub-Series: 3: - hab. Jan Barciszewski

RNA Biochemistry and Biotechnology

NATO Science Partnership Sub-Series: 3:

By: hab. Jan Barciszewski (Editor), Brian F. C. Clark (Editor)

Paperback

Published: 1st August 1999
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RNA Biochemistry and Biotechnology describes various aspects of nucleic acid and protein structure, mainly RNA structure and proteins, interacting with specific RNA species. Papers deal with DNA protein interactions, telomerase, aminoacyl-tRNA synthetases, elongation factor Tu, DNA repair, RNA structure, NMR technology, RNA aptamer interaction of biological macromolecules with metal ions. Two papers deal with theoretical aspects of RNA structure production and computer modelling. Many papers describe the possibility of commercial application of RNA biotechnology. One article discusses the impact of direct democracy on basic science supporting biotechnology.
Readership: Advanced graduate students, Ph.D. students and young scientists as well as specialists in the field.

Preface
List of Contributors
Why RNA?
Algorithms and thermodynamics for RNA secondary structure prediction: a practical guide
Recurrent RNA motifs: Analysis at the basepair level
Towards the 3D structure of 5S rRNA
Structure and dynamics of adenosine loops in RNA bulge duplexes. RNA hydration at the bulge site
The structure and function of the ribozyme RNAse P RNA is dictated by magnesium(II) ions
Metal ion-induced cleavages in probing of RNA structure
Protein-DNA recognition
Specific interaction between damaged bases in DNA and repair enzymes
Telomeric DNA recognition
Recognition of one tRNA by two classes of aminoacyl-tRNA synthetase
Functional structures of class-I-aminoacyl-tRNA synthetases
Aminoacylation of tRNA induces a conformational switch on the 3'-terminal ribose
Point mutants of elongation factor Tu from E. coli impaired in binding aminoaycl-tRNA
RNA structure and RNA-protein recognition during regulation of eukaryotic gene expression
RNA-aptamers for studying RNA-protein interactions
Probing of ribonucleoprotein complexes with site-specifically derivatized RNAs
The IRE model for families of RNA structures: Selective recognition by binding proteins (IRPs), NMR spectroscopy and probing with metal coordination complexes
Functional analysis of RNA signals in the HIV-1 genome by forced evolution
Interaction of native RNAs with Tat peptides
Biogenesis, structure and function of small nucleolar RNAs
RNA structure modules with trinucleotide repeat motifs
Phosphorothioate oligonucleotides as aptamers of retroviral reverse transcriptases
Oxathiaphospholane method of the stereocontrolled cynthesis of phosphorothioate analogues of oligonucleotides
Towards improved applications of cell-free protein biosynthesis endash, the influence of mRNA structure and suppressor tRNAs on the efficiency of the system
RNA on the web
How risky is direct democracy for basic science?
Subject Index
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780792358626
ISBN-10: 0792358627
Series: NATO Science Partnership Sub-Series: 3:
Audience: Professional
Format: Paperback
Language: English
Number Of Pages: 370
Published: 1st August 1999
Country of Publication: NL
Dimensions (cm): 23.62 x 15.75  x 2.29
Weight (kg): 0.59