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Risk Factors in Coronary Artery Disease : Fundamental and Clinical Cardiology - P. K. Shah

Risk Factors in Coronary Artery Disease

Fundamental and Clinical Cardiology

By: P. K. Shah (Editor)

Hardcover Published: 13th April 2006
ISBN: 9780824740955
Number Of Pages: 218

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Promoting developments in the diagnosis, prevention, and treatment of coronary artery disease, this reference furnishes the latest information on new and emerging risk factors for atherothrombotic vascular disorders-analyzing lipid-related and psychosocial risk factors, the genetic aspects of disease, the potential role of infection and inflammation, metabolic syndrome and insulin resistance, and elevated blood levels of homocysteine and hemostatic factors.

Series Introductionp. iii
Prefacep. v
Contributorsp. xi
Metabolic Syndrome and Cardiovascular Disease: Epidemiology, Pathophysiology, and Therapeutic Considerationsp. 1
Introductionp. 1
Metabolic Syndrome and Cardiovascular Disease Morbidity and Mortalityp. 3
Visceral Obesityp. 6
Insulin Resistancep. 11
Dyslipidemiap. 13
Hypertensionp. 17
Fibrinolytic Dysfunction, Endothelial Dysfunction, C-Reactive Proteinp. 19
Microalbuminuriap. 23
Abnormal Uric Acid Metabolismp. 24
Summaryp. 25
Referencesp. 26
Lipoprotein Metabolism and Implications for Atherosclerosis Risk Determination and Treatment Decisionsp. 35
Introductionp. 35
Basic Lipoprotein Metabolismp. 36
Classic Lipoprotein Disordersp. 43
Advanced Lipoprotein Disordersp. 47
Advances in Treatmentp. 58
Role of Noninvasive Testsp. 62
Conclusionp. 65
Referencesp. 67
Hemostatic Risk Factors for Atherothrombosisp. 85
Coagulation Factors and Atherothrombotic Diseasep. 85
Conclusionp. 89
Referencesp. 89
Homocysteine: A Risk Factor for Atherothrombotic Cardiovascular Diseasep. 95
Homocysteine Metabolismp. 96
Homocysteine: Circulating Formsp. 96
Homocysteine: Laboratory Measurementsp. 98
The Oral Methionine Loadp. 99
Determinants of Elevated Homocysteinep. 100
Homocysteine and Atherothrombosis: Pathophysiologic Mechanismsp. 101
Significance of Homocysteine Concentration in Acute Atherothrombotic Eventsp. 105
Epidemiological Evidence for Homocysteine and Atherothrombotic Diseasep. 106
Does Reduction of Elevated Homocysteine Impact Atherothrombotic Disease?p. 109
Conclusionp. 113
Referencesp. 114
Inflammation, Inflammatory Markers, and Cardiovascular Riskp. 121
Introductionp. 121
Role of Inflammation in Atherogenesis, Plaque Disruption, and Thrombosisp. 122
Systemic Markers of Inflammation and Cardiovascular Riskp. 123
Conclusionp. 129
Referencesp. 129
Chronic Infections as Risk Factors for Atherothrombosisp. 135
Introductionp. 135
Viral Infections and Atherothrombosisp. 136
Bacterial Infections and Vascular Diseasep. 137
Chlamydia pneumoniaep. 137
Helicobacter pylorip. 139
Periodontal Disease, Porphyromonas gingivalis, Streptococcus sanguis, and Atherothrombosisp. 140
Potential Role of Multiple Infectious Organismsp. 140
Potential Mechanisms by Which Infections May Predispose to Atherothrombosisp. 141
Summaryp. 143
Referencesp. 143
Novel Psychosocial Factors and Cardiovascular Diseasep. 151
Introductionp. 151
Depression and Cardiovascular Diseasep. 153
Social Supportp. 154
Psychosocial Factors and Traditional Cardiovascular Risk Factor Clusteringp. 154
Psychosocial Factors and Atherosclerosisp. 155
Psychosocial Factors and Endothelial Functionp. 155
Psychosocial Factors and Myocardial Ischemiap. 156
Psychosocial Factors and Plaque Rupturep. 156
Psychosocial Factors and Thrombosisp. 157
Psychosocial Factors and Lethal Arrhythmiasp. 157
Psychosocial Factors and Inflammationp. 158
Psychosocial Intervention Trialsp. 158
Summaryp. 159
Referencesp. 160
Genetic Risk Assessment Strategies for Coronary Artery Diseasep. 169
Introductionp. 169
Role of Genetics in Development and Progression of CADp. 169
Genetic Risk Assessment Strategies to Assess CAD and MI Susceptibilityp. 170
Approach to Individuals with High Familial Riskp. 181
Synopsisp. 186
Summaryp. 187
Referencesp. 187
Oxidants and Antioxidantsp. 199
The Antioxidative Defense and Lipid Oxidationp. 200
Lipid Oxidation in Atherosclerosisp. 201
Epidemiological Studies of Antioxidants and Cardiovascular Diseasep. 204
Referencesp. 207
Indexp. 211
Table of Contents provided by Ingram. All Rights Reserved.

ISBN: 9780824740955
ISBN-10: 0824740955
Series: Fundamental and Clinical Cardiology
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 218
Published: 13th April 2006
Country of Publication: US
Dimensions (cm): 22.84 x 16.23  x 2.01
Weight (kg): 0.51
Edition Number: 1

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