Review of Organic Functional Groups

5th Edition - Introduction to Medicinal Organic Chemistry

By: Victoria F. Roche

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Paperback | 13 January 2011 | Edition Number 5

At a Glance

Paperback
208 Pages

Edition Type
Revised

Dimensions(cm)
22 x 15 x 1

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With its Student Workbook CD-ROM and new case studies, the Fifth Edition of this acclaimed self-paced review enables students to master the principles and applications of organic functional groups. Moreover, it prepares students for the required pharmacy courses in medicinal chemistry by thoroughly covering nomenclature, physical properties, chemical properties, and metabolism. As students progress through the text, they will develop such important skills as drawing chemical structures and predicting the solubility, instabilities, and metabolism of each organic functional group.

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Preface	p. iii
Water Solubility and Chemical Bonding	p. 1
Van der Waals Attraction (Forces)	p. 2
Dipole-Dipole Bonding (Hydrogen Bond)	p. 2
Ionic Attraction	p. 3
Ion-Dipole Bonding	p. 4
Alkanes (C_nH_2n+2	p. 6
Alkenes (C_nH_2n	p. 11
Cycloalkanes: Alkene Isomers	p. 13
Aromatic Hydrocarbons	p. 16
Haolgenated Hydrocarbons	p. 19
Case Studies	p. 21
Alcohols	p. 23
Case Studies	p. 27
Phenols	p. 29
Case Studies	p. 34
Ethers and Thioethers	p. 36
Ethers	p. 36
Thioethers	p. 38
Case Studies	p. 40
Aldehydes and Ketones	p. 42
Case Studies	p. 47
Amines
Amines-General	p. 49
Quaternary Ammonium Salts	p. 58
Case Studies	p. 59
Carboxylic Acids	p. 62
Case Studies	p. 70
Functional Derivatives of Carboxylic Acids	p. 73
Esters	p. 73
Amides	p. 76
Carbonates, Carbamates, and Ureas	p. 79
Amidines and Guanidines	p. 81
Case Studies	p. 82
Sulfonic Acids and Sulfonamides	p. 85
Sulfonic Acids	p. 85
Sulfonamides	p. 86
Case Studies	p. 87
Nitrogen Functional Groups	p. 90
Nitro Groups	p. 90
Nitrate Group	p. 90
Nitrite Group	p. 91
Oximes	p. 92
Hydrazone/Hydrazine/Hydrazide	p. 92
Case Studies	p. 93
Heterocycles	p. 96
Three-Membered Ring Heterocycles	p. 96
Four-Membered Ring Heterocycles	p. 99
Five-Membered Ring Heterocycles	p. 100
Five-Membered Ring Heterocycles with Two or More Heteroatoms	p. 105
Six-Membered Ring Heterocycles	p. 112
Saturated Six-Membered Ring Heterocycles	p. 119
Seven- and Eight-Membered Ring Heterocycles	p. 120
Bicyclic Heterocycles: Five-Membered Ring Plus Six-Membered Ring	p. 120
Bicyclic Heterocycles: Six-Membered Ring Plus Six-Membered Ring	p. 125
Bicyclic Heterocycles: Six-Membered Ring Plus Seven-Membered Ring	p. 128
Tricyclic Heterocycles	p. 129
Case Studies	p. 130
Oligonucleotides and Nucleic Acids	p. 133
Case Studies	p. 138
Proteins	p. 141
Case Studies	p. 151
Predicting Water Solubility	p. 153
The Role of Chemical Bonding between Dissimilar Organic Functional Groups	p. 153
Empiric Method for Predicting Water Solubility	p. 156
Analytic Method for Calculating Water Solubility	p. 160
Case Studies	p. 162
Stereoisomerism-Asymmetric Molecules	p. 164
Acidity and Basicity	p. 167
Definitions of Acids and Bases	p. 167
Relative Strengths of Acids and Bases	p. 169
Reaction of an Acid with a Base in Water	p. 171
Acidic and Basic Organic Function Groups	p. 173
Drug Metabolism	p. 176
Metabolic Enzymes	p. 176
Learning Objectives	p. 184
Glossary	p. 187
Index	p. 189
Table of Contents provided by Ingram. All Rights Reserved.

Review of Organic Functional Groups

5th Edition - Introduction to Medicinal Organic Chemistry

At a Glance

Paperback

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How to return your order

Defective items

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