Restorative Therapies in Parkinson's Disease

By: Patrik Brundin (Editor), C. Warren Olanow (Editor)

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Hardcover | 5 July 2006

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404 Pages

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23.39 x 15.6 x 2.39

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In this exciting and timely book new approaches to repairing the brains of people suffering from Parkinson's disease are described by leading experts. Never in history has there been greater hope that novel experimental therapies can support significant restoration of brain function. Restorative therapy that can be applied in large numbers of patients does not yet exist, but the initial trials have provided a fundamental insight into the potential for plasticity in the diseased brain. This book gives an overview of the current state-of-the-art research for brain repair, what the challenges are, and an indication of what research can provide for the next generation of people with Parkinson's disease. The comprehensive chapters are geared to an audience of neuroscientists, neurologists, neurosurgeons and anyone interested in how findings in the research laboratory can effectively be transferred to the clinic.

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Non-Fiction Medicine Clinical & Internal Medicine Neurology & Clinical Neurophysiology Surgery Science Biology, Life Sciences Life Sciences in General Neurosciences

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Published: 19th September 2014

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Restorative therapies for Parkinson's disease : current status and future perspectives	p. 1
Restorative therapies for Parkinson's disease : ethical issues	p. 12
Evolution of Parkinson's disease and treatment requirements : what new treatments are needed and the role of striatal grafting	p. 50
Clinical trial design issues	p. 65
Lessons learned from early clinical neural grafting in Parkinson's disease	p. 78
Fetal nigral transplantation as a therapy for Parkinson's disease	p. 93
Imaging of the Parkinsonian brain in relation to restorative therapy	p. 119
Important aspects of surgical methodology for transplantation in Parkinson's disease	p. 131
Histopathological and clinical criteria for analyzing transplanted human dopamine cells in Parkinson's disease	p. 166
Dyskinesias and neural grafting in Parkinson's disease	p. 184
Porcine neural xenotransplantation : current status	p. 225
Adult-derived stem cells for transplantation in Parkinson's disease	p. 244
Embryonic stem cells for grafting in Parkinson's disease	p. 269
Genetically modified cells as a source for grafting in Parkinson's disease	p. 285
Delivery of GDNF for Parkinson's disease : transition of a neuroprotective treatment strategy from basic sciences to clinical application	p. 297
In vivo gene therapy as a potential treatment for Parkinson's disease	p. 317
Table of Contents provided by Blackwell. All Rights Reserved.

Restorative Therapies in Parkinson's Disease

At a Glance

Hardcover

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How to return your order

Defective items

You Can Find This Book In

Other Editions and Formats

Paperback

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