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Research in Computational Molecular Biology : 14th Annual International Conference, RECOMB 2010, Lisbon, Portugal, April 25-28, 2010, Proceedings - Bonnie G. Berger

Research in Computational Molecular Biology

14th Annual International Conference, RECOMB 2010, Lisbon, Portugal, April 25-28, 2010, Proceedings

By: Bonnie G. Berger (Editor)

Paperback Published: 20th April 2010
ISBN: 9783642126826
Number Of Pages: 582

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This volume contains the papers presented at RECOMB 2010: the 14th Annual International Conference on Research in Computational Molecular Biology held in Lisbon, Portugal, during April 25-28, 2010. The RECOMB conference series was started in 1997 by Sorin Istrail, Pavel Pevzner, and Michael Waterman. RECOMB 2010 was hosted by INESC-ID and Instituto Superior Tecnico, or- nized by a committee chaired by Arlindo Oliveira and took place at the Int- national Fair of Lisbon Meeting Centre. This year, 36 papers were accepted for presentation out of 176 submissions. The papers presented were selected by the Program Committee (PC) assisted by a number of external reviewers. Each paper was reviewed by three members of the PC, or by external reviewers, and there was an extensive Web-based discussion over a period of two weeks, leading to the ?nal decisions. RECOMB 2010 also introduced a Highlights Track, in which six additional presentations by senior authors were chosen from papers published in 2009. The RECOMB conferenceseriesiscloselyassociatedwiththeJournalofComputational Biology, which traditionally publishes special issues devoted to presenting full versions of selected conference papers.

An Algorithmic Framework for Predicting Side-Effects of Drugsp. 1
SubMAP: Aligning Metabolic Pathways with Subnetwork Mappingsp. 15
Admixture Aberration Analysis: Application to Mapping in Admixed Population Using Pooled DNAp. 31
Pathway-Based Functional Analysis of Metagenomesp. 50
Hierarchical Generative Biclustering for MicroRNA Expression Analysisp. 65
Subnetwork State Functions Define Dysregulated Subnetworks in Cancerp. 80
Proteome Coverage Prediction for Integrated Proteomics Datasetsp. 96
Discovering Regulatory Overlapping RNA Transcriptsp. 110
Alignment-Free Phylogenetic Reconstructionp. 123
Inference of Isoforms from Short Sequence Reads (Extended Abstract)p. 138
The Clark Phase-able Sample Size Problem: Long-Range Phasing and Loss of Heterozygosity in GWASp. 158
A New Algorithm for Improving the Resolution of Cryo-EM Density Mapsp. 174
Towards Automated Structure-Based NMR Resonance Assignmentp. 189
Gapped Spectral Dictionaries and Their Applications for Database Searches of Tandem Mass Spectrap. 208
naiveBayesCall: An Efficient Model-Based Base-Calling Algorithm for High-Throughput Sequencingp. 233
Extracting Between-Pathway Models from E-MAP Interactions Using Expected Graph Compressionp. 248
Simultaneous Identification of Causal Genes and Dys-Regulated Pathways in Complex Diseasesp. 263
Incremental Signaling Pathway Modeling by Data Integrationp. 281
The Poisson Margin Test for Normalisation Free Significance Analysis of NGS Datap. 297
Compressing Genomic Sequence Fragments Using SLIMGENEp. 310
On the Genealogy of Asexual Diploidsp. 325
Genovo: De Novo Assembly for Metagenomesp. 341
MoGUL: Detecting Common Insertions and Deletions in a Populationp. 357
Generalized Buneman Pruning for Inferring the Most Parsimonious Multi-state Phytogenyp. 369
Seed Design Framework for Mapping SOLiD Readsp. 384
Accurate Estimation of Expression Levels of Homologous Genes in RNA-seq Experimentsp. 397
Cactus Graphs for Genome Comparisonsp. 410
IDBA - A Practical Iterative de Bruijn Graph De Novo Assemblerp. 426
Predicting Nucleosome Positioning Using Multiple Evidence Tracksp. 441
Dense Subgraphs with Restrictions and Applications to Gene Annotation Graphsp. 456
Time and Space Efficient RNA-RNA Interaction Prediction via Sparse Foldingp. 473
HLA Type Inference via Haplotypes Identical by Descentp. 491
Algorithms for Detecting Significantly Mutated Pathways in Cancerp. 506
Leveraging Sequence Classification by Taxonomy-Based Multitask Learningp. 522
A Novel Abundance-Based Algorithm for Binning Metagenomic Sequences Using l-Tuplesp. 535
A Markov Random Field Framework for Protein Side-Chain Resonance Assignmentp. 550
Genomic DNA k-mer Spectra: Models and Modalities (Abstract)p. 571
Deciphering the Swine-Flu Pandemics of 1918 and 2009 (Abstract)p. 572
Distinguishing Direct versus Indirect Transcription Factor-DNA Interactions (Abstract)p. 574
A Self-regulatory System of Interlinked Signaling Feedback Loops Controls Mouse Limb Patterning (Abstract)p. 575
Automated High-Dimensional Flow Cytometric Data Analysis (Abstract)p. 577
Discovering Transcriptional Modules by Combined Analysis of Expression Profiles and Regulatory Sequences (Abstract)p. 578
Author Indexp. 581
Table of Contents provided by Ingram. All Rights Reserved.

ISBN: 9783642126826
ISBN-10: 3642126820
Series: Lecture Notes in Computer Science
Audience: General
Format: Paperback
Language: English
Number Of Pages: 582
Published: 20th April 2010
Publisher: Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg
Country of Publication: DE
Dimensions (cm): 23.37 x 15.75  x 3.05
Weight (kg): 0.91